Variables Associated with Change in Quality of Life among Persons with Dementia in Nursing Homes: A 10 Months Follow-Up Study

被引：35
作者：
Mjorud, Marit [1 ]
Rosvik, Janne [1 ]
Rokstad, Anne Marie Mork [2 ]
Kirkevold, Marit [3 ]
Engedal, Knut [1 ]
机构：
[1] Vestfold Hosp Trust, Norwegian Ctr Ageing & Hlth, Tonsberg, Norway
[2] Vestfold Hosp Trust, Molde Univ Coll, Norwegian Ctr Ageing & Hlth, Tonsberg, Norway
[3] Univ Oslo, Dept Nursing Sci, Inst Hlth & Soc, Oslo, Norway
来源：
PLOS ONE | 2014年 / 9卷 / 12期
关键词：
ALZHEIMERS-DISEASE; DEPRESSIVE SYMPTOMS; PEOPLE; CARE; PREVALENCE; SCALE; CHALLENGES; RESIDENTS;
D O I：
10.1371/journal.pone.0115248
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Aim: To investigate variables associated with change in quality of life (QOL), measured by QUALID scale and three subscales; tension, sadness and wellbeing, among dementia patients in nursing homes. Method: A 10 months follow-up study including 198 (female 156, 79%) nursing home patients, mean age 87 (s.d 7.7) years. Scales applied; quality of life in late stage dementia (QUALID) scale and three subscales (wellbeing, sadness and tension), neuropsychiatric inventory questionnaire 10 items (NPI-10-Q), clinical dementia rating (CDR) scale, physical self-maintenance (PSMS) scale and a scale of general medical health. Use of psychotropic medication, gender and age was collected from the patient's records. Results: Mean baseline QUALID score: 20.6 (s.d. 7.0), follow-up score: 22.9 (s.d. 7.4), mean change 2.8 (s.d. 7.4). QOL improved in 30.8%, were unchanged in 14.7%, deteriorated in 54.6% of patients. A regression analysis revealed that change in QUALID score was significantly associated with: QUALID baseline score (beta -.381, p-value. 000), change in NPI score (beta. 421, p-value. 000), explained variance 38.1%. Change in score on wellbeing subscale associated with: change in PSMS score (beta. 185, p-value. 019), wellbeing baseline score (beta -.370, p-value. 000), change in NPI score (beta. 186, p-value. 017), explained variance 25.3%. Change in score on tension subscale associated with: change in CDR sum-of-boxes (beta. 214, p-value. 003), change in NPI score (beta. 270, p-value. 000), tension baseline score (beta -.423, p-value. 000), explained variance 34.6%. Change in score on sadness subscale associated with: change in NPI score (beta. 404, p-value. 000), sadness baseline score (beta -.438, p-value.000), explained variance 38.8%. Conclusion: The results imply that a lower baseline score (better QOL) results in a larger change in QOL (towards worse QOL). Change in QOL is mostly associated with change in neuropsychiatric symptoms. In almost 50% of patients QOL did not deteriorate.
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页数：17
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