A little-known new components of the appetite control

被引：0

作者：

Nylec, Marcin ^{[1
]}

Olszanecka-Glinianowicz, Magdalena ^{[1
]}

机构：

[1] Slaskiego Uniwersytetu Med, Katedry Patofizjol, Zaklad Promocji Zdrowia & Leczenia Otylosci, PL-40752 Katowice, Poland

来源：

POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ | 2010年 / 64卷

关键词：

appetite control; QRFP-43; TLQP-21; xenin; VGF-DERIVED PEPTIDE; FOOD-INTAKE; HYPOTHALAMIC NEUROPEPTIDE; OREXIGENIC ACTIVITY; RFAMIDE PEPTIDES; ENERGY-BALANCE; BODY-WEIGHT; XENIN; RATS; OBESITY;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Appetite control is a complex process regulated by both neurotransmitters, such as: appetite-increasing neuropeptide Y (NPY), Agouti related peptide (AgRP), orexins A and B, as well as appetite-suppressing propiomelanocortin (POMC) and a peptide (CART) which transcription is regulated by cocaine and amphetamine. In addition, other factors are involved such as hormones of the alimentary tract (appetite-stimulating ghrelin and appetite-decreasing cholecystokinin, peptide YY, glucagon like peptide-1, oxyntomodulin, pancreatic peptide, enterostatin and amylin). In this process participates also leptin, an appetite-suppressing hormone produced by adipocytes. The authors focus on other, little-known neurotransmitters involved in the control of appetite: RFamide Peptide (QRFP43) and VGF-Derived Peptide, TLQP-21, as well as xenin, another hunger-decreasing hormone of the alimentary tract.

引用

收藏

页码：291 / 295

页数：5

相关论文

共 44 条

[1] Xenin - a novel suppressor of food intake in rats [J].

Alexiou, C ;

Zimmermann, JP ;

Schick, RR ;

Schusdziarra, V .

BRAIN RESEARCH, 1998, 800 (02) :294-299

[2] Localization of xenin-immunoreactive cells in the duodenal mucosa of humans and various mammals [J].

Anlauf, M ;

Weihe, E ;

Hartschuh, W ;

Hamscher, G ;

Feurle, GE .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 2000, 48 (12) :1617-1626

[3] TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity [J].

Bartolomucci, A. ;

La Corte, G. ;

Possenti, R. ;

Locatelli, V. ;

Rigamonti, A. E. ;

Torsello, A. ;

Bresciani, E. ;

Bulgarelli, I. ;

Rizzi, R. ;

Pavone, F. ;

D'Amato, F. R. ;

Severini, C. ;

Mignogna, G. ;

Giorgi, A. ;

Schinina, M. E. ;

Elia, G. ;

Brancia, C. ;

Ferri, G. -L. ;

Conti, R. ;

Ciani, B. ;

Pascucci, T. ;

Dell'Omo, G. ;

Muller, E. E. ;

Levi, A. ;

Moles, A. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (39) :14584-14589

[4] Suppression of QRFP 43 in the hypothalamic ventromedial nucleus of Long-Evans rats fed a high-fat diet [J].

Beck, Bernard ;

Richy, Sebastien .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 383 (01) :78-82

[5] Identification of 26RFa from frog brain - A novel hypothalamic neuropeptide with orexigenic activity in mammals [J].

Chartrel, N ;

Bruzzone, F ;

Dujardin, C ;

Leprince, J ;

Tollemer, H ;

Anouar, Y ;

Vallarino, M ;

Costentin, J ;

Vaudry, H .

TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY, 2005, 1040 :80-83

[6] Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity [J].

Chartrel, N ;

Dujardin, C ;

Anouar, Y ;

Leprince, J ;

Decker, A ;

Clerens, S ;

Do-Régo, JC ;

Vandesande, F ;

Llorens-Cortes, C ;

Costentin, J ;

Beauvillain, JC ;

Vaudry, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (25) :15247-15252

[7] Xenin reduces feed intake by activating the ventromedial hypothalamus and influences gastrointestinal transit rate in chicks [J].

Cline, Mark A. ;

Nandar, Wint ;

Rogers, J. Orion .

BEHAVIOURAL BRAIN RESEARCH, 2007, 179 (01) :28-32

[8] Oxyntomodulin suppresses appetite and reduces food intake in humans [J].

Cohen, MA ;

Ellis, SM ;

Le Roux, CW ;

Batterham, RL ;

Park, A ;

Patterson, M ;

Frost, GS ;

Ghatei, MA ;

Bloom, SR .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (10) :4696-4701

[9] Melanocortins and body weight: a tale of two receptors [J].

Cummings, DE ;

Schwartz, MW .

NATURE GENETICS, 2000, 26 (01) :8-9

[10] Behavioral effects of 26RFamide and related peptides [J].

do Rego, Jean-Claude ;

Leprince, Jerome ;

Chartrel, Nicolas ;

Vaudry, Hubert ;

Costentin, Jean .

PEPTIDES, 2006, 27 (11) :2715-2721

← 1 2 3 4 5 →