Prognostic factors and survival in patients with squamous cell carcinoma lymph nodes metastases from an unknown primary to the head and neck

被引：0

作者：

Zhuang, Shi-Min ^{[1
]}

Zhang, Ji ^{[2
]}

Chen, Shu-Wei ^{[2
]}

Li, Huan ^{[2
]}

Song, Ming ^{[2
]}

机构：

[1] Sun Yat Sen Univ, Affiliated Hosp 6, Dept Otolaryngol Head & Neck Surg, Guangzhou 510060, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Ctr Canc, State Key Lab Oncol South China, Dept Head & Neck Surg,Collaborat Innovat Ctr Canc, 651 Dongfeng Dong Rd, Guangzhou 510060, Guangdong, Peoples R China

来源：

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2016年 / 9卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Cervical lymph node metastases; unknown primary tumor; squamous cell carcinoma; radiotherapy; surgery; CERVICAL METASTASES; RADIATION-THERAPY; PRIMARY TUMORS; MANAGEMENT; RADIOTHERAPY; ORIGIN;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Purpose: To analyze the clinicopathological characteristics, treatment modalities, and potential prognostic factors of cancer of unknown primary tumor (CUP) in a consecutivegroup cases. Methods: This retrospective study enrolled consecutive patients who were admitted to the Sun Yat-senUniversity Cancer Center between 1980 and 2011. Results: The key prognostic factors influencing the survival were the lymph nodes extracapsular extension (ECE), N classification, recurrence, emergence of primary tumor and treatment modalities. Multivariate analysis revealed that N classification and recurrence were independent risk factor for patient survival. Conclusions: N classification and recurrence were independent prognostic factor that influenced the treatment outcome. Our data indicate that combined surgery and postoperative radiotherapy for CUP offers the best chance for long-term survival.

引用

页码：5828 / 5834

页数：7

共 19 条

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