Synthesis of 1-((5-oxo-4,5-Dihydro-1,3,4-oxadiazol-2-yl)methyl)-1H-1,2,4-triazole-3-carboxylic Acid-Application of Antibacterial activity

被引:0
作者
Brahmayya, Manuri [1 ,2 ,3 ]
Samsonu, Dasi [4 ]
Rao, Alaparthi Venkateswara [5 ]
Rao, Nelli Srinivasa [6 ]
Rao, Battula Venkateswara [1 ]
Fan, Huan-Jung [3 ]
机构
[1] Andhra Univ, Dept Engn Chem, Visakhapatnam, Andhra Pradesh, India
[2] Natl Chung Hsing Univ, Dept Chem Engn, Taichung, Taiwan
[3] HungKuang Univ, Dept Environm Engn Safety & Hlth, Taichung, Taiwan
[4] Andhra Univ, Dept Organ Chem & FDW, Visakhapatnam, Andhra Pradesh, India
[5] KL Univ, Adv Funct Mat Res Ctr, Dept Phys, Guntur, Andhra Pradesh, India
[6] Natl Chiao Tung Univ, Dept Mat Sci & Engn, Hsinchu 300, Taiwan
基金
英国科研创新办公室;
关键词
1; 2; 4-Triazole; Sodium methoxide; Hydrazine monohydrate; Hydrazide; Carbon dioxide; 3; 4-Oxadiazole; 1,3,4-OXADIAZOLES; 1,3,4-THIADIAZOLES; DERIVATIVES;
D O I
10.1007/s40010-018-0507-5
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Synthesis of 1-((5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl) methyl)-1H-1,2,4-triazole-3-carboxylic acid was accomplished starting with the commercially available 1,2,4-triazole-3-carboxylic acid. The conversion of hydrazide and carbon dioxide to 1,3,4-oxadiazole has been explained. Antibacterial activity also studied for some synthesized compounds.
引用
收藏
页码:621 / 627
页数:7
相关论文
共 20 条
[1]   Synthesis and anticonvulsant activity of new 2-substituted-5-[2-(2-fluorophenoxy)phenyl]-1,3,4-oxadiazoles and 1,2,4-triazoles [J].
Almasirad, A ;
Tabatabai, SA ;
Faizi, M ;
Kebriaeezadeh, A ;
Mehrabi, N ;
Dalvandi, A ;
Shafiee, A .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2004, 14 (24) :6057-6059
[2]   Synthesis of 5-substituted-3H-[1,3,4]-oxadiazol-2-one derivatives: a carbon dioxide route (CDR) [J].
Brahmayya, M. ;
Dai, Shenghong A. ;
Suen, S. -Y. .
RSC ADVANCES, 2015, 5 (80) :65351-65357
[3]   Novel procedure for the synthesis of 1,3,4-oxadiazoles from 1,2-diacylhydrazines using polymer-supported Burgess reagent under microwave conditions [J].
Brain, CT ;
Paul, JM ;
Loong, Y ;
Oakley, PJ .
TETRAHEDRON LETTERS, 1999, 40 (16) :3275-3278
[4]   Substituent effect on photophysical properties of bi-1,3,4-oxadiazole derivatives in solution [J].
Chen, Fangyi ;
Tian, Taiji ;
Zhao, Chengxiao ;
Bai, Binglian ;
Li, Min ;
Wang, Haitao .
JOURNAL OF MOLECULAR STRUCTURE, 2016, 1109 :239-246
[5]   Synthesis characterization and anticancer activity studies on some Mannich bases derived from 1,2,4-triazoles [J].
Holla, BS ;
Veerendra, B ;
Shivananda, MK ;
Poojary, B .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2003, 38 (7-8) :759-767
[6]   Rapid side-chain chlorination of heterocyclic compounds using focused microwave irradiation [J].
Kidwai, M ;
Kohli, S ;
Kumar, P .
JOURNAL OF CHEMICAL RESEARCH-S, 1998, (09) :586-587
[7]   Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists [J].
Kim, Jong Yup ;
Seo, Hee Jeong ;
Lee, Sung-Han ;
Jung, Myung Eun ;
Ahn, Kwangwoo ;
Kim, Jeongmin ;
Lee, Jinhwa .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (01) :142-145
[8]   Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds [J].
Küçükgüzel, SG ;
Oruç, EE ;
Rollas, S ;
Sahin, F ;
Özbek, A .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2002, 37 (03) :197-206
[9]   1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: Synthesis and preliminary evaluation of biological properties [J].
Kumar, Harish ;
Javed, Sadique A. ;
Khan, Suroor A. ;
Amir, Mohammad .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (12) :2688-2698
[10]   Efficient phosphonium-mediated synthesis of 2-amino-1,3,4-oxadiazoles [J].
Levins, Christopher G. ;
Wan, Zhao-Kui .
ORGANIC LETTERS, 2008, 10 (09) :1755-1758