Rotator cuff tear healing process with graft augmentation of fascia lata in a rabbit model

被引：27

作者：

Kataoka, Takeshi ^{[1
]}

Kokubu, Takeshi ^{[1
]}

Muto, Tomoyuki ^{[1
]}

Mifune, Yutaka ^{[1
]}

Inui, Atsuyuki ^{[1
]}

Sakata, Ryosuke ^{[1
]}

Nishimoto, Hanako ^{[1
]}

Harada, Yoshifumi ^{[1
]}

Takase, Fumiaki ^{[1
]}

Ueda, Yasuhiro ^{[1
]}

Kurosawa, Takashi ^{[1
]}

Yamaura, Kohei ^{[1
]}

Kuroda, Ryosuke ^{[1
]}

机构：

[1] Kobe Univ, Dept Orthopaed Surg, Grad Sch Med, Chuo Ku, 7-5-1 Kusunoki Cho, Kobe, Hyogo 6500017, Japan

来源：

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH | 2018年 / 13卷

关键词：

Large and massive rotator cuff tear; Fascia lata augmentation; Type III collagen; Ultimate failure load; SUPRASPINATUS TENDON; ARTHROSCOPIC REPAIR; MASSIVE TEARS; INTEGRITY; ROW; COLLAGEN; BONE; ANTERIOR; OUTCOMES;

D O I：

10.1186/s13018-018-0900-4

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Background: Fascia lata augmentation of massive rotator cuff tears has shown good clinical results. However, its biological effect during the early healing process is not clearly understood. The purpose of the study was to evaluate the biological efficacy of fascia lata augmentation during the early healing process of rotator cuff tears using a rabbit rotator cuff defect model. Methods: The infraspinatus tendon was resected from the greater tuberosity of a rabbit to create a rotator cuff tear. The tendon edge was directly sutured to the humeral head. The rotator cuff repaired site was augmented with a fascia lata autograft (augmentation group, group A). The rotator cuff defect in the contralateral shoulder was repaired without augmentation (reattachment group, group R). A group with intact rotator cuff was set as the control group. Histological examinations and mechanical analysis were conducted 4 and 8 weeks postoperatively. Results: In the HE staining, the tendon maturing score of group A was higher than that of group R at 4 weeks postoperatively. In the safranin O staining, proteoglycan staining at the repaired enthesis in group A at 4 weeks postoperatively was stronger than that in group R. Picrosirius red staining showed that type III and type I collagen in group A was more strongly expressed than that in group R at 4 weeks postoperatively. The ultimate failure load of the infraspinatus tendon-humeral head complex in group A was statistically higher than that in group R at 4 weeks postoperatively. The ultimate failure load of group A was similar to that of the control group. Conclusion: The biological and mechanical contribution of fascia lata augmentation for massive rotator cuff tears was analyzed in this study. Type III collagen was reported to be expressed during the tendon healing process. Although the biological action similar to natural ligament healing occurred around the fascia lata grafts, type III collagen was gradually replaced by type I collagen as the tissue matured. Our results suggest that fascia lata augmentation could stimulate biological healing and provide initial fixation strength of the repaired rotator cuff.

引用

页数：9

共 30 条

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