Enzymatic kinetic resolution of α-hydroxysilanes

被引：6

作者：

An, Ilhwan ^{[1
]}

Onyeozili, Edith N. ^{[2
]}

Maleczka, Robert E., Jr. ^{[1
]}

机构：

[1] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA

[2] Florida A&M Univ, Dept Chem, Tallahassee, FL 32307 USA

来源：

TETRAHEDRON-ASYMMETRY | 2010年 / 21卷 / 05期

关键词：

SECONDARY ALCOHOLS; ALPHA; BETA-UNSATURATED ACYLSILANES; ORGANOSILICON COMPOUNDS; EFFICIENT SYNTHESIS; ORGANIC-SOLVENT; IONIC LIQUIDS; VINYL ESTERS; LIPASE; REARRANGEMENT; ESTERIFICATION;

D O I：

10.1016/j.tetasy.2010.02.030

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The enzymatic kinetic resolution of alpha-hydroxysilanes where the silicon bears a variety of substituents has been explored. Reactions were performed on various alpha-hydroxysilanes with several commercially available enzymes, solvents, acetylation reagents, and temperatures. The resulting optically active alpha-hydroxysilanes and their corresponding acetates were obtained in varying yields and ees. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：527 / 534

页数：8

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