Qualitative analysis of a chemostat model with inhibitory exponential substrate uptake

被引:16
作者
Fu, GF [1 ]
Ma, WB
Ruan, SG
机构
[1] Univ Sci & Technol Beijing, Appl Sci Coll, Dept Math & Mech, Beijing 100083, Peoples R China
[2] Univ Miami, Dept Math, Coral Gables, FL 33124 USA
基金
中国国家自然科学基金;
关键词
D O I
10.1016/j.chaos.2004.05.049
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
In this paper, we consider a simple chemostat model involving a single species feeding on redundant substrate with a constant yield term. Many experiments indicate that very high substrate concentrations actually inhibit growth. Instead of assuming the prevalent Monod kinetics for growth rate of cells, we use a non-monotonic functional response function to describe the inhibitory effect. A detailed qualitative analysis about the local and global stability of its equilibria (including all critical cases) is carried out. Numerical simulations are performed to show that the dynamical properties depend intimately upon the parameters. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:873 / 886
页数:14
相关论文
共 13 条
[1]  
Beretta E., 1994, Differential Equations and Dynamical Systems, V2, P263
[2]  
Chen L. S., 1993, Nonlinear Biological Dynamical System
[3]   THE EFFECT OF THE SPECIFIC GROWTH-RATE AND YIELD EXPRESSIONS ON THE EXISTENCE OF OSCILLATORY BEHAVIOR OF A CONTINUOUS FERMENTATION MODEL [J].
CROOKE, PS ;
WEI, CJ ;
TANNER, RD .
CHEMICAL ENGINEERING COMMUNICATIONS, 1980, 6 (06) :333-347
[4]  
Edoardo B., 1994, Differential Equations and Dynamical Systems, V2, P19
[5]   A theoretical and empirical investigation of delayed growth response in the continuous culture of bacteria [J].
Ellermeyer, S ;
Hendrix, J ;
Ghoochan, N .
JOURNAL OF THEORETICAL BIOLOGY, 2003, 222 (04) :485-494
[6]   LIMIT-CYCLES IN A CHEMOSTAT-RELATED MODEL [J].
KUANG, Y .
SIAM JOURNAL ON APPLIED MATHEMATICS, 1989, 49 (06) :1759-1767
[7]  
MA Z, 2001, QUALITATIVE ANAL STA
[8]  
Perko L., 1996, DIFFER EQUAT DYN SYS, DOI DOI 10.1007/978-1-4684-0249-0
[9]   Multiple limit cycles in the chemostat with variable yield [J].
Pilyugin, SS ;
Waltman, P .
MATHEMATICAL BIOSCIENCES, 2003, 182 (02) :151-166
[10]   Bifurcation analysis of a chemostat model with a distributed delay [J].
Ruan, SG ;
Wolkowicz, GSK .
JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS, 1996, 204 (03) :786-812