Mechanisms of regulation of lysosomal thiol protease activity in thyroid gland: Effects of protein synthesis inhibitors

被引：0
作者：
Stroev, EA [1 ]
Kochukov, MY [1 ]
机构：
[1] IP Pavlov Med Univ, Dept Biol & Bioorgan Chem, Ryazan, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1997年 / 123卷 / 05期
关键词：
lysosomal cysteine proteases; thyroid gland; triiodothyronine; regulation;
D O I：
10.1007/BF02445316
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Triiodothyronine administered for 7 days reduces the contents of total cathepsin B and L (but not cathepsin C) in rat thyroid gland. Cycloheximide reduces the contents of cathepsins B, C, and L, while actinomycin D induces a less pronounced decrease in cathepsin C and L activity, cathepsin B activity being unchanged. Against the background of triiodothyronine, both agents equally inhibit these proteases.
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页码：453 / 455
页数：3
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