Goodness-of-fit tests for modeling longitudinal ordinal data

Longitudinal studies involving categorical responses are extensively applied in many fields of research and are often fitted by the generalized estimating equations (GEE) approach and generalized linear mixed models (GLMMs) The assessment of model fit is an important issue for model inference The purpose of this article is to extend Pan's (2002a) goodness-of-fit tests for GEE models with longitudinal binary data to the tests for logistic proportional odds models with longitudinal ordinal data Two proposed methods based on Pearson chi-squared test and unweighted sum of residual squares are developed, and the approximate expectations and variances of the test statistics are easily computed Four major variants of working correlation structures, independent, AR(1), exchangeable and unspecified, are considered to estimate the variances of the proposed test statistics Simulation studies in terms of type I error rate and the power performance of the proposed tests are presented for various sample sizes Furthermore, the approaches are demonstrated by two real data sets. (C) 2010 Elsevier B V All rights reserved