Timing of advanced airway management by emergency medical services personnel following out-of-hospital cardiac arrest: A population-based cohort study

被引:43
作者
Izawa, Junichi [1 ,2 ]
Iwami, Taku [3 ]
Gibo, Koichiro [4 ]
Okubo, Masashi [5 ]
Kajino, Kentaro [6 ]
Kiyohara, Kousuke [7 ]
Nishiyama, Chika [8 ]
Nishiuchi, Tatsuya [9 ]
Hayashi, Yasuyuki [10 ]
Kiguchi, Takeyuki [3 ]
Kobayashi, Daisuke [3 ]
Komukai, Sho [11 ]
Kawamura, Takashi [3 ]
Callaway, Clifton W. [5 ]
Kitamura, Tetsuhisa [12 ]
机构
[1] Jikei Univ, Sch Med, Dept Anesthesiol, Intens Care Unit, Tokyo, Japan
[2] Univ Pittsburgh, Dept Crit Care Med, Ctr Crit Care Nephrol, Pittsburgh, PA USA
[3] Kyoto Univ, Dept Hlth Serv, Kyoto, Japan
[4] Okinawa Chubu Hosp, Dept Emergency Med, Uruma, Okinawa, Japan
[5] Univ Pittsburgh, Dept Emergency Med, Pittsburgh, PA USA
[6] Kansai Med Univ, Dept Emergency & Crit Care Med, Osaka, Japan
[7] Tokyo Womens Med Univ, Dept Publ Hlth, Tokyo, Japan
[8] Kyoto Univ, Dept Crit Care Nursing, Grad Sch Human Hlth Sci, Kyoto, Japan
[9] Amagasaki Gen Med Ctr, Dept Emergency & Gen Med, Osaka, Japan
[10] Osaka Saiseikai Senri Hosp, Senri Crit Care Med Ctr, Osaka, Japan
[11] Saga Univ Hosp, Clin Res Ctr, Saga, Japan
[12] Osaka Univ, Grad Sch Med, Dept Social & Environm Med, Div Environm Med & Populat Sci, 1-1 Yamada Oka, Suita, Osaka 5650871, Japan
关键词
Emergency medical technicians; Heart arrest; Intubation; EUROPEAN RESUSCITATION COUNCIL; AMERICAN-HEART-ASSOCIATION; INTERNATIONAL LIAISON COMMITTEE; HEALTH-CARE PROFESSIONALS; ILLNESS SEVERITY SCORE; CARDIOPULMONARY-RESUSCITATION; TRACHEAL INTUBATION; LIFE-SUPPORT; ENDOTRACHEAL INTUBATION; UTSTEIN TEMPLATES;
D O I
10.1016/j.resuscitation.2018.04.024
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Early prehospital advanced airway management (AAM) by emergency medical services (EMS) personnel has been intended to improve patient outcomes from out-of-hospital cardiac arrest (OHCA). However, few studies examine the effectiveness of early prehospital AAM. We investigated whether early prehospital AAM was associated with functionally favourable survival after adult OHCA. Methods: We conducted a population-based cohort study of OHCA in Osaka, Japan, between 2005 and 2012. We included all consecutive, non-traumatic adult OHCA in which EMS personnel performed cardiopulmonary resuscitation (CPR) and AAM. Main exposure was time from CPR to AAM. Primary outcome was functionally favourable survival at one-month. As the primary analysis, we estimated adjusted odds ratio (OR) of time from CPR to AAM using multivariable logistic regression in the original cohort. In the secondary analysis, we divided the time from CPR to AAM into early (0-4 min) and late (5-29 min). We calculated propensity scores (PS) for early AAM and performed PS-matching. Results: We included 27,471 patients who received prehospital AAM by EMS personnel. In this original cohort, time from CPR to AAM was inversely associated with functionally favourable survival (adjusted OR 0.90 for oneincrement of minute, 95% confidence interval [CI] 0.87-0.94). In the PS-matched cohort of 17,022 patients, early AAM, compared to late AAM, was associated with functionally favourable survival: 2.2% vs 1.4%; adjusted OR 1.58 (95% CI 1.24-2.02). Conclusions: Earlier prehospital AAM by EMS personnel was associated with functionally better survival among adult patients who received AAM.
引用
收藏
页码:16 / 23
页数:8
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