Platelet lipidomics and function: joining the dots

被引:11
作者
McFadyen, James D. [1 ,2 ,3 ]
Peter, Karlheinz [1 ,2 ,3 ]
机构
[1] Baker Heart & Diabet Inst, Melbourne, Vic, Australia
[2] Alfred Hosp, Melbourne, Vic, Australia
[3] Monash Univ, Clayton, Vic, Australia
关键词
EXPOSURE;
D O I
10.1182/blood-2018-06-854950
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this issue of Blood, Peng et al use a quantitative lipidomics platform, comprising mass spectrometry, network analysis, and in vitro studies to provide a comprehensive quantitative analysis of the platelet lipidome. This study sheds new light on how the platelet lipidome is altered during platelet activation and, importantly, how changes in the platelet lipidome may modulate platelet function.
引用
收藏
页码:465 / +
页数:4
相关论文
共 7 条
  • [1] Stereochemistry- and concentration-dependent effects of phosphatidylserine enrichment on platelet function
    Meyer, Audrey F.
    Gruba, Sarah M.
    Kim, Donghyuk
    Meyer, Ben M.
    Koseoglu, Secil
    Dalluge, Joseph J.
    Haynes, Christy L.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2017, 1859 (08): : 1381 - 1387
  • [2] An Enigmatic Case of Acute Mercury Poisoning: Clinical, Immunological Findings and Platelet Function
    Kleffner, Ilka
    Eichler, Susann
    Ruck, Tobias
    Schuengel, Lisa
    Pfeuffer, Steffen
    Polzer, Philipp
    Dittrich, Ralf
    Dziewas, Rainer
    Gross, Catharina C.
    Goebel, Kerstin
    Wiendl, Heinz
    Kehrel, Beate E.
    Meuth, Sven G.
    FRONTIERS IN NEUROLOGY, 2017, 8
  • [3] Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function
    Roka-Moiia, Yana
    Ammann, Kaitlyn R.
    Miller-Gutierrez, Samuel
    Sheriff, Jawaad
    Bluestein, Danny
    Italiano, Joseph E.
    Flaumenhaft, Robert C.
    Slepian, Marvin J.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (08)
  • [4] Artificial cerebrospinal fluid restores aspirin-inhibited physiological hemostasis through recovery of platelet aggregation function
    Suzuki, Ryosuke
    Kozuma, Yukinori
    Inoue, Chisako
    Tanabe, Kano
    Noboruo, Ippei
    Arao, Hohomi
    Kawaguchi, Tatsuya
    Shimizu, Nobuyuki
    Yamamoto, Tetsuya
    ACTA NEUROCHIRURGICA, 2023, 165 (05) : 1269 - 1276
  • [5] Impact of heat-not-burn cigarette passive smoking on children's oxidative stress, endothelial and platelet function
    Loffredo, Lorenzo
    Carnevale, Roberto
    Pannunzio, Arianna
    Cinicola, Bianca Laura
    Palumbo, Ilaria Maria
    Bartimoccia, Simona
    Nocella, Cristina
    Cammisotto, Vittoria
    Violi, Francesco
    Biondi-Zoccai, Giuseppe
    Frati, Giacomo
    Zicari, Anna Maria
    ENVIRONMENTAL POLLUTION, 2024, 345
  • [6] The Differential Effect of Carbon Dots on Gene Expression and DNA Methylation of Human Embryonic Lung Fibroblasts as a Function of Surface Charge and Dose
    Sima, Michal
    Vrbova, Kristyna
    Zavodna, Tana
    Honkova, Katerina
    Chvojkova, Irena
    Ambroz, Antonin
    Klema, Jiri
    Rossnerova, Andrea
    Polakova, Katerina
    Malina, Tomas
    Belza, Jan
    Topinka, Jan
    Rossner, Pavel, Jr.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (13) : 1 - 23
  • [7] Insights into CdTe quantum dots induced hepatotoxicity: Regulation of cytochromes P450 isoenzymes function in liver microsomes from in vivo and in vitro studies
    Li, Jiayi
    Li, Ao
    Luo, Kui
    Yang, Hong
    Jiang, Shuqin
    Huang, Peili
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2025, 768