Fluorescence-guided surgery for high-grade gliomas

被引:61
|
作者
Lakomkin, Nikita [1 ,2 ]
Hadjipanayis, Constantinos G. [1 ,2 ]
机构
[1] Mt Sinai Hlth Syst, Icahn Sch Med Mt Sinai, Dept Neurosurg, New York, NY USA
[2] Mt Sinai Hlth Syst, Mt Sinai Beth Israel, Icahn Sch Med, Dept Neurosurg, New York, NY USA
关键词
5-aminolevulinic acid (5-ALA); glioblastoma multiforme (GBM); photodynamic therapy; INDUCED PROTOPORPHYRIN-IX; INTERSTITIAL PHOTODYNAMIC THERAPY; COMBINING 5-AMINOLEVULINIC ACID; MALIGNANT BRAIN-TUMORS; OF-THE-LITERATURE; GLIOBLASTOMA-MULTIFORME; INTRAOPERATIVE FLUORESCENCE; PHASE-II; IN-VITRO; RESECTION;
D O I
10.1002/jso.25154
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5-aminolevulinic acid (5-ALA) is a prodrug that results in the fluorescence of high-grade gliomas relative to the surrounding brain parenchyma. 5-ALA has been increasingly utilized in fluorescence-guided surgery for these tumors, and its intraoperative use has been associated with a significantly improved extent of resection and progression-free survival. This review outlines the growing body of evidence that has culminated in the recent Food and Drug Administration approval of 5-ALA, as well as emerging applications for this agent.
引用
收藏
页码:356 / 361
页数:6
相关论文
共 50 条
  • [21] Intraoperative image-guided surgery in neuro-oncology with specific focus on high-grade gliomas
    Mahboob, Syed O.
    Eljamel, Muftah
    FUTURE ONCOLOGY, 2017, 13 (26) : 2349 - 2361
  • [22] The Evolution of Fluorescence-Guided Surgery
    Van Keulen, Stan
    Hom, Marisa
    White, Haley
    Rosenthal, Eben L.
    Baik, Fred M.
    MOLECULAR IMAGING AND BIOLOGY, 2023, 25 (01) : 36 - 45
  • [23] Exoscopic versus Microscopic Surgery in 5-ALA-Guided Resection of High-Grade Gliomas
    Garufi, Giada
    Conti, Alfredo
    Chaurasia, Bipin
    Cardali, Salvatore Massimiliano
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (12)
  • [24] Fluorescence-guided resections of malignant gliomas using 5-ALA
    Stummer, Walter
    2010 7TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, 2010, : 1003 - 1005
  • [25] Fluorescence-guided surgery of brain abscesses
    Hoehne, Julius
    Brawanski, Alexander
    Schebesch, Karl-Michael
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2017, 155 : 36 - 39
  • [26] Fluorescence-guided surgery for liver tumors
    Nakaseko, Yuichi
    Ishizawa, Takeaki
    Saiura, Akio
    JOURNAL OF SURGICAL ONCOLOGY, 2018, 118 (02) : 324 - 331
  • [27] Identification of PEPT2 as an important candidate molecule in 5-ALA-mediated fluorescence-guided surgery in WHO grade II/III gliomas
    Hou, Chongxian
    Yamaguchi, Shigeru
    Ishi, Yukitomo
    Terasaka, Shunsuke
    Kobayashi, Hiroyuki
    Motegi, Hiroaki
    Hatanaka, Kanako C.
    Houkin, Kiyohiro
    JOURNAL OF NEURO-ONCOLOGY, 2019, 143 (02) : 197 - 206
  • [28] Chemotherapy for high-grade gliomas
    Galanis, E
    Buckner, J
    BRITISH JOURNAL OF CANCER, 2000, 82 (08) : 1371 - 1380
  • [29] Impact of Intraoperative Neurophysiological Monitoring on Surgery of High-Grade Gliomas
    Kombos, Theodoros
    Picht, Thomas
    Derdilopoulos, Athanasios
    Suess, Olaf
    JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2009, 26 (06) : 422 - 425
  • [30] Chemotherapy for high-grade gliomas
    E Galanis
    J Buckner
    British Journal of Cancer, 2000, 82 : 1371 - 1380