High-throughput siRNA screens using γH2AX as marker uncover key regulators of genome integrity in mammalian cells

被引:4
作者
Beck, Halfdan [1 ]
Menzel, Tobias [1 ]
Syljuasen, Randi G. [2 ]
Sorensen, Claus Storgaard [1 ]
机构
[1] Univ Copenhagen, BRIC, Copenhagen N, Denmark
[2] Oslo Univ Hosp, Norwegian Radium Hosp, Inst Canc Res, Dept Radiat Biol, Oslo, Norway
关键词
genome integrity; DNA damage; gamma H2AX; RNAi screening; siRNA library;
D O I
10.4161/cc.9.12.12017
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:2257 / 2258
页数:2
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