Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides

被引：12
|
作者：
El Arba, Marie [1 ]
Dibrell, Sara E. [1 ]
Meece, Frederick [1 ]
Frantz, Doug E. [1 ]
机构：
[1] Univ Texas San Antonio, Dept Chem, San Antonio, TX 78249 USA
来源：
ORGANIC LETTERS | 2018年 / 20卷 / 18期
基金：
美国国家科学基金会;
关键词：
POLYSUBSTITUTED FURANS; MULTISUBSTITUTED FURANS; REGIOSELECTIVE SYNTHESIS; DIAZOCARBONYL COMPOUNDS; CATALYTIC CONVERSION; ORGANIC-SYNTHESIS; NATURAL-PRODUCTS; ALKYNES; CYCLIZATION; PYRROLES;
D O I：
10.1021/acs.orglett.8b02554
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of densely functionalized trisubstituted and tetrasubstituted furans via a novel Ru(II)-catalyzed intramolecular cyclization of vinyl diazoesters is reported. The synthetic utility of these furans is further demonstrated through a simple acid-mediated reaction to access highly substituted Delta alpha,beta-butenolides.
引用
收藏
页码：5886 / 5888
页数：3
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