Ru(II)-Catalyzed Synthesis of Substituted Furans and Their Conversion to Butenolides

被引：12

作者：

El Arba, Marie ^{[1
]}

Dibrell, Sara E. ^{[1
]}

Meece, Frederick ^{[1
]}

Frantz, Doug E. ^{[1
]}

机构：

[1] Univ Texas San Antonio, Dept Chem, San Antonio, TX 78249 USA

来源：

ORGANIC LETTERS | 2018年 / 20卷 / 18期

基金：

美国国家科学基金会;

关键词：

POLYSUBSTITUTED FURANS; MULTISUBSTITUTED FURANS; REGIOSELECTIVE SYNTHESIS; DIAZOCARBONYL COMPOUNDS; CATALYTIC CONVERSION; ORGANIC-SYNTHESIS; NATURAL-PRODUCTS; ALKYNES; CYCLIZATION; PYRROLES;

D O I：

10.1021/acs.orglett.8b02554

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of densely functionalized trisubstituted and tetrasubstituted furans via a novel Ru(II)-catalyzed intramolecular cyclization of vinyl diazoesters is reported. The synthetic utility of these furans is further demonstrated through a simple acid-mediated reaction to access highly substituted Delta alpha,beta-butenolides.

引用

页码：5886 / 5888

页数：3

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