Reducing activity of polyphenols with stable radicals of the TTM series.: Electron transfer versus H-abstraction reactions in flavan-3-ols

被引：70
作者：
Jiménez, A
Selga, A
Torres, JU
Julia, L
机构：
[1] CSIC, IIQAB, Dept Quim Peptids & Prot, ES-08034 Barcelona, Spain
[2] CSIC, IIQAB, Dept Quim Organ Biol, ES-08034 Barcelona, Spain
来源：
ORGANIC LETTERS | 2004年 / 6卷 / 24期
关键词：
D O I：
10.1021/ol048015f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] A new method to test the antioxidant activity of polyphenols by electron transfer reactions to a stable organic free radical, tris(2,4,6-trichloro-3,5-dinitrophenyl)methyl radical (HNTTM), is reported. Therefore, the activity of the natural flavanols, (-)-epicatechin, and two synthetic derivatives, 4beta-(S-cysteinyl)epicatechin and 4beta-(2-aminoethylthio)epicatechin, can be differentiated by their capacity to transfer hydrogen atoms to 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) and to transfer electrons to HNTTM.
引用
收藏
页码：4583 / 4586
页数：4
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