Gluten-Free Diet in Children with Autism Spectrum Disorders: A Randomized, Controlled, Single-Blinded Trial

被引：34

作者：

Piwowarczyk, Anna ^{[1
]}

Horvath, Andrea ^{[2
]}

Pisula, Ewa ^{[3
]}

Kawa, Rafal ^{[3
]}

Szajewska, Hania ^{[2
]}

机构：

[1] Med Univ Warsaw, Dept Paediat, Clin Assessment Unit, Zwirki Wigury 63a, PL-02091 Warsaw, Poland

[2] Med Univ Warsaw, Dept Paediat, Zwirki Wigury 63A, PL-02091 Warsaw, Poland

[3] Univ Warsaw, Fac Psychol, Dept Hlth & Rehabil Psychol, Stawki 5-7, PL-00183 Warsaw, Poland

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2020年 / 50卷 / 02期

关键词：

Randomized controlled trial; Autism spectrum disorder; Children; Gluten; GASTROINTESTINAL DISORDERS; INTERVENTIONS; DIAGNOSIS; SYMPTOMS;

D O I：

10.1007/s10803-019-04266-9

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

To determine whether a gluten-free diet (GFD) compared with a gluten-containing diet (GD) influences functioning of children with autism spectrum disorders (ASD), we performed a randomized, controlled, single-blinded trial. Sixty-six children (36-69 months) with ASD, within the normal IQ (> 70) range, who had been on a GFD for at least 8 weeks before enrollment were eligible for inclusion. After an 8-week run-in period on a GFD, the GFD group continued this diet and the GD group consumed at least one normal meal containing gluten per day for 6 months. There were no differences between groups in autistic symptoms, maladaptive behaviors, or intellectual abilities after the intervention. A GFD compared with a GD did not affect functioning of children with ASD. Trial registration ClinicalTrials.gov, number NCT02280746.

引用

页码：482 / 490

页数：9

共 38 条

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