Mitigating Lung Fibrosis by Targeting Dysfunctional Alveolar Epithelial Cell Lipid Metabolism

被引:5
作者
Kamp, David W. [1 ,2 ]
机构
[1] Northwestern Univ, Div Pulm & Crit Care Med, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Jesse Brown VA Med Ctr, Chicago, IL 60612 USA
关键词
IDIOPATHIC PULMONARY-FIBROSIS; DISEASE;
D O I
10.1165/rcmb.2018-0070ED
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:139 / 140
页数:2
相关论文
共 16 条
[1]   Surfactant Lipids at the Host-Environment Interface Metabolic Sensors, Suppressors, and Effectors of Inflammatory Lung Disease [J].
Fessler, Michael B. ;
Summer, Ross S. .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2016, 54 (05) :624-635
[2]   The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis [J].
Kim, Seok-Jo ;
Cheresh, Paul ;
Jablonski, Renea P. ;
Williams, David B. ;
Kamp, David W. .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2015, 16 (09) :21486-21519
[3]   Endoplasmic reticulum stress in the pathogenesis of fibrotic disease [J].
Kropski, Jonathan A. ;
Blackwell, Timothy S. .
JOURNAL OF CLINICAL INVESTIGATION, 2018, 128 (01) :64-73
[4]   Idiopathic pulmonary fibrosis [J].
Martinez, Fernando J. ;
Collard, Harold R. ;
Pardo, Annie ;
Raghu, Ganesh ;
Richeldi, Luca ;
Selman, Moises ;
Swigris, Jeffrey J. ;
Taniguchi, Hiroyuki ;
Wells, Athol U. .
NATURE REVIEWS DISEASE PRIMERS, 2017, 3
[5]   Pulmonary fibrosis in the era of stratified medicine [J].
Mathai, Susan K. ;
Newton, Chad A. ;
Schwartz, David A. ;
Garcia, Christine Kim .
THORAX, 2016, 71 (12) :1154-1160
[6]   Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span [J].
Misharin, Alexander V. ;
Morales-Nebreda, Luisa ;
Reyfman, Paul A. ;
Cuda, Carla M. ;
Walter, James M. ;
McQuattie-Pimentel, Alexandra C. ;
Chen, Ching-I ;
Anekalla, Kishore R. ;
Joshi, Nikita ;
Williams, Kinola J. N. ;
Abdala-Valencia, Hiam ;
Yacoub, Tyrone J. ;
Chi, Monica ;
Chiu, Stephen ;
Gonzalez-Gonzalez, Francisco J. ;
Gates, Khalilah ;
Lam, Anna P. ;
Nicholson, Trevor T. ;
Homan, Philip J. ;
Soberanes, Saul ;
Dominguez, Salina ;
Morgan, Vince K. ;
Saber, Rana ;
Shaffer, Alexander ;
Hinchcliff, Monique ;
Marshall, Stacy A. ;
Bharat, Ankit ;
Berdnikovs, Sergejs ;
Bhorade, Sangeeta M. ;
Bartom, Elizabeth T. ;
Morimoto, Richard I. ;
Balch, William E. ;
Sznajder, Jacob I. ;
Chandel, Navdeep S. ;
Mutlu, Gokhan M. ;
Jain, Manu ;
Gottardi, Cara J. ;
Singer, Benjamin D. ;
Ridge, Karen M. ;
Bagheri, Neda ;
Shilatifard, Ali ;
Budinger, G. R. Scott ;
Perlman, Harris .
JOURNAL OF EXPERIMENTAL MEDICINE, 2017, 214 (08) :2387-2404
[7]   Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis [J].
Mora, Ana L. ;
Bueno, Marta ;
Rojas, Mauricio .
JOURNAL OF CLINICAL INVESTIGATION, 2017, 127 (02) :405-414
[8]   Mortality from pulmonary fibrosis increased in the United States from 1992 to 2003 [J].
Olson, Amy L. ;
Swigris, Jeffrey J. ;
Lezotte, Dennis C. ;
Norris, Jill M. ;
Wilson, Carla G. ;
Brown, Kevin K. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2007, 176 (03) :277-284
[9]   Mitochondrial Dysfunction in Pulmonary Fibrosis [J].
Rangarajan, Sunad ;
Bernard, Karen ;
Thannickal, Victor J. .
ANNALS OF THE AMERICAN THORACIC SOCIETY, 2017, 14 :S383-S388
[10]   Lipid Synthesis Is Required to Resolve Endoplasmic Reticulum Stress and Limit Fibrotic Responses in the Lung [J].
Romero, Freddy ;
Hong, Xu ;
Shah, Dilip ;
Kallen, Caleb B. ;
Rosas, Ivan ;
Guo, Zhi ;
Schriner, DeLeila ;
Barta, Julie ;
Shaghaghi, Hoora ;
Hoek, Jan B. ;
Mesaros, Clementine ;
Choi, Augustine M. ;
Snyder, Nathaniel W. ;
Summer, Ross .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2018, 59 (02) :225-236