The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue

被引：224
作者：
Ciosek, Zaneta [1 ]
Kot, Karolina [2 ]
Kosik-Bogacka, Danuta [3 ]
Lanocha-Arendarczyk, Natalia [2 ]
Rotter, Iwona [1 ]
机构：
[1] Pomeranian Med Univ, Dept Med Rehabil & Clin Physiotherapy, Zolnierska 54, PL-71210 Szczecin, Poland
[2] Pomeranian Med Univ, Dept Biol & Med Parasitol, Powstancow Wielkopolskich 72, PL-70111 Szczecin, Poland
[3] Pomeranian Med Univ, Independent Lab Pharmaceut Bot, Powstancow Wielkopolskich 72, PL-70111 Szczecin, Poland
来源：
BIOMOLECULES | 2021年 / 11卷 / 04期
关键词：
bone; calcium; fluorine; lead; magnesium; phosphorus;
D O I：
10.3390/biom11040506
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bones are metabolically active organs. Their reconstruction is crucial for the proper functioning of the skeletal system during bone growth and remodeling, fracture healing, and maintaining calcium-phosphorus homeostasis. The bone metabolism and tissue properties are influenced by trace elements that may act either indirectly through the regulation of macromineral metabolism, or directly by affecting osteoblast and osteoclast proliferation or activity, or through becoming part of the bone mineral matrix. This study analyzes the skeletal impact of macroelements (calcium, magnesium, phosphorus), microelements (fluorine), and heavy metals (lead), and discusses the concentration of each of these elements in the various bone tissues.
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页数：26
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