Chemiluminescent method for determination of tetracycline, chlortetracycline, minocycline, doxycycline, and demeclocycline

被引：1

作者：

Marczynski, S ^{[1
]}

机构：

[1] Tech Univ Szczecin, Inst Phys, PL-70310 Szczecin, Poland

来源：

BIOPOLYMERS | 2000年 / 57卷 / 06期

关键词：

chemiluminescence; tetracyclines; photon counting; half-life;

D O I：

10.1002/1097-0282(2000)57:6<365::AID-BIP60>3.0.CO;2-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A chemiluminescent method is described for the determination of tetracycline, chlortetracycline, minocycline, doxycycline, and demeclocycline. The method is based on the photon counting technique and the spline functions approximation. The simple formula S = b + Ax(2) is proposed for the observed dependency of the integrated number of countings S on the concentration x of a given antibiotic. The correlation between S and the half-life of a drug in the human body is proved. (C) 2000 John Wiley & Sons, Inc.

引用

页码：365 / 372

页数：8

共 8 条

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