Evaluating Microalbuminuria in Children with Sickle Cell Disease: Review of the Literature

被引：0

作者：

Speller-Brown, Barbara ^{[1
]}

Anderson, Claire ^{[2
]}

Tuchman, Shamir ^{[3
,4
]}

Wang Yunfei ^{[3
,4
]}

Mistry, Kirtida ^{[3
,4
]}

Martin, Brenda ^{[3
]}

Frantz, Amy ^{[3
]}

Coons, Joshua ^{[5
]}

Darbari, Deepika S. ^{[3
,4
]}

机构：

[1] Childrens Natl Hlth Syst, Washington, DC 20010 USA

[2] Great North Childrens Hosp, Newcastle Upon Tyne, Tyne & Wear, England

[3] Childrens Natl Hlth Syst, Ctr Canc & Blood Disorders, Washington, DC USA

[4] George Washington Univ, Sch Med & Hlth Sci, Washington, DC 20052 USA

[5] Eastern Virginia Med Sch, Washington, DC USA

来源：

JNP-JOURNAL FOR NURSE PRACTITIONERS | 2018年 / 14卷 / 10期

关键词：

kidney; microalbuminuria; proteinuria; screening; sickle cell disease; KIDNEY-DISEASE; BLOOD-PRESSURE; RENAL-FAILURE; RISK-FACTORS; ANEMIA; ALBUMINURIA; PREVALENCE; HEMOLYSIS; ADULTS; NEPHROPATHY;

D O I：

10.1016/j.nurpra.2018.08.008

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Microalbuminuria, an early marker of renal injury, may begin early in sickle cell disease (SCD). We conducted a retrospective chart review of 205 patients with SCD. Clinical data and treatment regimens were reviewed. Data were analyzed to determine prevalence and correlates of microalbuminuria and proteinuria. Thirty-one patients (15.2%) had microalbuminuria. Proteinuria, hematuria, age, height, weight, and systolic blood pressure were significantly associated with microalbuminuria. Age was the strongest predictor. We propose that all children with SCD be screened by annual urinalysis and careful blood pressure monitoring at each clinic visit for early identification of children at risk for renal injury. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：739 / 744

页数：6

共 30 条

[11]

Bolarinwa RA, 2012, SAUDI J KIDNEY DIS T, V23, P171

[12] Association between hemolysis and albuminuria in adults with sickle cell anemia [J].

Day, Thomas G. ;

Drasar, Emma R. ;

Fulford, Tony ;

Sharpe, Claire C. ;

Thein, Swee Lay .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2012, 97 (02) :201-205

[13] Kidney Disease among Patients with Sickle Cell Disease, Hemoglobin SS and SC [J].

Drawz, Paul ;

Ayyappan, Sabarish ;

Nouraie, Mehdi ;

Saraf, Santosh ;

Gordeuk, Victor ;

Hostetter, Thomas ;

Gladwin, Mark T. ;

Little, Jane .

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2016, 11 (02) :207-215

[14] Chronic kidney disease is common in sickle cell disease: a cross-sectional study in the Tema Metropolis, Ghana [J].

Ephraim, Richard Kobina Dadzie ;

Osakunor, Derick Nii Mensah ;

Cudjoe, Obed ;

Oduro, Enos Amoako ;

Asante-Asamani, Lyudmila ;

Mitchell, Juliana ;

Agbodzakey, Hope ;

Adoba, Prince .

BMC NEPHROLOGY, 2015, 16

[15] Proteinuria is associated with elevated tricuspid regurgitant jet velocity in children with sickle cell disease [J].

Forrest, Suzanne ;

Kim, Ashley ;

Carbonella, Judith ;

Pashankar, Farzana .

PEDIATRIC BLOOD & CANCER, 2012, 58 (06) :937-940

[16] Glomerular involvement in adults with sickle cell hemoglobinopathies: Prevalence and clinical correlates of progressive renal failure [J].

Guasch, Antonio ;

Navarrete, Jose ;

Nass, Kaleed ;

Zayas, Carlos F. .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 17 (08) :2228-2235

[17] Albuminuria correlates with hemolysis and NAG and KIM-1 in patients with sickle cell anemia [J].

Hamideh, Dima ;

Raj, Vimal ;

Harrington, Thomas ;

Li, Hua ;

Margolles, Emilio ;

Amole, Folasade ;

Garcia-Buitrago, Monica ;

Ruiz, Phillip ;

Zilleruelo, Gaston ;

Alvarez, Ofelia .

PEDIATRIC NEPHROLOGY, 2014, 29 (10) :1997-2003

[18]

Herrick James B., 2001, Yale Journal of Biology and Medicine, V74, P179

[19] Hydroxyurea is associated with lower prevalence of albuminuria in adults with sickle cell disease [J].

Laurin, Louis-Philippe ;

Nachman, Patrick H. ;

Desai, Payal C. ;

Ataga, Kenneth I. ;

Derebail, Vimal K. .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2014, 29 (06) :1211-1218

[20] Sickle cell disease: renal manifestations and mechanisms [J].

Nath, Karl A. ;

Hebbel, Robert P. .

NATURE REVIEWS NEPHROLOGY, 2015, 11 (03) :161-171

← 1 2 3 →