Evaluating Microalbuminuria in Children with Sickle Cell Disease: Review of the Literature

被引：0

作者：

Speller-Brown, Barbara ^{[1
]}

Anderson, Claire ^{[2
]}

Tuchman, Shamir ^{[3
,4
]}

Wang Yunfei ^{[3
,4
]}

Mistry, Kirtida ^{[3
,4
]}

Martin, Brenda ^{[3
]}

Frantz, Amy ^{[3
]}

Coons, Joshua ^{[5
]}

Darbari, Deepika S. ^{[3
,4
]}

机构：

[1] Childrens Natl Hlth Syst, Washington, DC 20010 USA

[2] Great North Childrens Hosp, Newcastle Upon Tyne, Tyne & Wear, England

[3] Childrens Natl Hlth Syst, Ctr Canc & Blood Disorders, Washington, DC USA

[4] George Washington Univ, Sch Med & Hlth Sci, Washington, DC 20052 USA

[5] Eastern Virginia Med Sch, Washington, DC USA

来源：

JNP-JOURNAL FOR NURSE PRACTITIONERS | 2018年 / 14卷 / 10期

关键词：

kidney; microalbuminuria; proteinuria; screening; sickle cell disease; KIDNEY-DISEASE; BLOOD-PRESSURE; RENAL-FAILURE; RISK-FACTORS; ANEMIA; ALBUMINURIA; PREVALENCE; HEMOLYSIS; ADULTS; NEPHROPATHY;

D O I：

10.1016/j.nurpra.2018.08.008

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Microalbuminuria, an early marker of renal injury, may begin early in sickle cell disease (SCD). We conducted a retrospective chart review of 205 patients with SCD. Clinical data and treatment regimens were reviewed. Data were analyzed to determine prevalence and correlates of microalbuminuria and proteinuria. Thirty-one patients (15.2%) had microalbuminuria. Proteinuria, hematuria, age, height, weight, and systolic blood pressure were significantly associated with microalbuminuria. Age was the strongest predictor. We propose that all children with SCD be screened by annual urinalysis and careful blood pressure monitoring at each clinic visit for early identification of children at risk for renal injury. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：739 / 744

页数：6

共 30 条

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