The emergence of new genes on the young therian X

被引：25

作者：

Potrzebowski, Lukasz ^{[1
]}

Vinckenbosch, Nicolas ^{[1
]}

Kaessmann, Henrik ^{[1
]}

机构：

[1] Univ Lausanne, Ctr Integrat Genom, CH-1015 Lausanne, Switzerland

来源：

TRENDS IN GENETICS | 2010年 / 26卷 / 01期

基金：

瑞士国家科学基金会;

关键词：

SEX-CHROMOSOMES; EVOLUTION; SEQUENCE;

D O I：

10.1016/j.tig.2009.11.001

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Recent studies have revealed that our sex chromosomes differentiated relatively recently from ancestral autosomes in the common ancestor of placental and marsupial mammals (therians). Here, we show that the therian X started to accumulate now retroduplicate genes with overall sex-biased expression upon therian sex chromosome differentiation. This process reached its peak within the first similar to 90 million years of sex chromosome evolution and then leveled off. Taken together, our observations suggest that the major sex-related functional remodeling of the X was completed relatively soon after the origination of therian sex chromosomes.

引用

页码：1 / 4

页数：4

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