Use of Plasma Procalcitonin Levels as an Adjunct to Clinical Microbiology

被引：105

作者：

Gilbert, David N. ^{[1
,2
]}

机构：

[1] Oregon Hlth & Sci Univ, Dept Med Educ, Providence Portland Med Ctr, Portland, OR 97213 USA

[2] Oregon Hlth & Sci Univ, Dept Med, Portland, OR 97213 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2010年 / 48卷 / 07期

关键词：

C-REACTIVE PROTEIN; RESPIRATORY-TRACT INFECTIONS; CALCITONIN-I GENE; ANTIBIOTIC-TREATMENT; SERUM PROCALCITONIN; BACTERIAL-INFECTION; DIAGNOSTIC MARKER; INFLAMMATION; BIOMARKERS; SEPSIS;

D O I：

10.1128/JCM.00655-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Procalcitonin (PCT) is synthesized by a large number of tissues and organs in response to invasion by pathogenic bacteria, fungi, and some parasites. Current PCT assays are rapid, specific, and of sufficient sensitivity to detect increases in PCT serum levels within 4 to 6 h of initiation of infection. Clinically, PCT levels may help in decisions regarding the need for empirical antibiotic therapy, "source control" of infection, and duration of antibiotic therapy. The addition of PCT levels to bacterial culture and viral detection results can assist with the separation of colonization and invasion by pathogenic bacteria.

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收藏

页码：2325 / 2329

页数：5

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