Advances in chromone-based reactants in the ring opening and skeletal reconstruction reaction: access to skeletally diverse salicyloylbenzene/heterocycle derivatives

被引:14
作者
Guo, Dong-Gui [1 ,2 ]
Wang, Hui-Juan [1 ]
Zhou, Ying [3 ]
Liu, Xiong-Li [1 ]
机构
[1] Guizhou Univ, Natl & Local Joint Engn Res Ctr Exploitat Homol R, Guiyang 550025, Guizhou, Peoples R China
[2] Guizhou Inst Technol, Coll Food & Pharmaceut Engn, Guiyang 550003, Guizhou, Peoples R China
[3] Guizhou Univ Chinese Med, Coll Pharmaceut Sci, Guiyang 550025, Guizhou, Peoples R China
基金
中国国家自然科学基金;
关键词
1,3-BIS(SILYL ENOL ETHERS); DIELS-ALDER REACTION; ONE-POT SYNTHESIS; REGIOSELECTIVE SYNTHESIS; DOMINO REACTIONS; DIMETHYL 1,3-ACETONEDICARBOXYLATE; FUNCTIONALIZED BENZOPHENONES; CONVENIENT SYNTHESIS; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS;
D O I
10.1039/d2ob00478j
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Salicyloylbenzene/heterocycles are privileged scaffolds found in many natural products and bioactive molecules. Numerous useful approaches for the preparation of these privileged scaffolds have been developed in recent years. Among these approaches, chromone-based reactants have demonstrated their importance in the synthesis of these salicyloylbenzene/heterocycle scaffolds with structural complexity and potential biological appeal. In this review, the recent advances in the synthesis of salicyloylbenzene/heterocycles are summarized and discussed according to the chromone-based reactants which could be achieved in one step via ring-opening and skeletal reconstruction reactions. Both the mechanisms and the applications of the corresponding products in organic and medicinal chemistry are also described.
引用
收藏
页码:4681 / 4698
页数:18
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