Malaria and its importance in travel medicine

被引：0

作者：

Mischlinger, Johannes ^{[1
,2
]}

Jochum, Johannes ^{[1
,2
]}

Ramharter, Michael ^{[3
,4
]}

Kurth, Florian ^{[2
,5
,6
]}

机构：

[1] Univ Klinikum Hamburg Eppendorf, Dept Trop Med, Hamburg, Germany

[2] Bernhard Nocht Inst Tropenmed, Bernhard Nocht Str 74, D-20359 Hamburg, Germany

[3] Univ Klinikum Hamburg Eppendorf, Med Klin 1, Sekt Tropenmed, Hamburg, Germany

[4] Bernhard Nocht Inst Tropenmed, Abt Klin Forsch, Hamburg, Germany

[5] Bernhard Nocht Inst Tropenmed, Dept Trop Med, Hamburg, Germany

[6] Charite, Berlin, Germany

来源：

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT | 2022年 / 147卷 / 12期

关键词：

malaria; falciparum; artemisinin; plasmodium; artesunate; ARTESUNATE; EUROPE;

D O I：

10.1055/a-1661-3783

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Malaria remains one of the most important infectious diseases worldwide. The annual number of cases is currently estimated at around 240 million globally, of which more than 500,000 cases are fatal. The majority of malaria cases in Europe are imported from the African continent. Plasmodium falciparum, the causative agent of malaria tropica, causes 75-90 % of all infections imported to Germany. Artemisinin-based combination therapies are the standard treatment for uncomplicated malaria worldwide. In addition to uncomplicated malaria infections, Plasmodium falciparum can cause severe malaria, characterized by vital organ dysfunction and hyperparasitaemia. The treatment of choice for severe malaria is parenteral artesunate. For all patients presenting with febrile illness after a stay in a malaria-endemic area malaria must be ruled out immediately. Microscopy of the thick drop remains the gold standard for diagnosis in clinical routine.

引用

页码：745 / 754

页数：10

共 20 条

[1] Evidence of Artemisinin-Resistant Malaria in Africa [J].

Balikagala, Betty ;

Fukuda, Naoyuki ;

Ikeda, Mie ;

Katuro, Osbert T. ;

Tachibana, Shin-Ichiro ;

Yamauchi, Masato ;

Opio, Walter ;

Emoto, Sakurako ;

Anywar, Denis A. ;

Kimura, Eisaku ;

Palacpac, Nirianne M. Q. ;

Odongo-Aginya, Emmanuel, I ;

Ogwang, Martin ;

Horii, Toshihiro ;

Mita, Toshihiro .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (13) :1163-1171

[2] Malaria diagnostics: now and the future [J].

Chiodini, Peter L. .

PARASITOLOGY, 2014, 141 (14) :1873-1879

[3]

Deutsche Gesellschaft fur Tropenmedizin Reisemedizin und Globale Gesundheit e.V. (DTG), 2021, LEITL DIAGN THER MAL

[4] Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial [J].

Dondorp, Arjen M. ;

Fanello, Caterina I. ;

Hendriksen, Ilse C. E. ;

Gomes, Ermelinda ;

Seni, Amir ;

Chhaganlal, Kajal D. ;

Bojang, Kalifa ;

Olaosebikan, Rasaq ;

Anunobi, Nkechinyere ;

Maitland, Kathryn ;

Kivaya, Esther ;

Agbenyega, Tsiri ;

Nguah, Samuel Blay ;

Evans, Jennifer ;

Gesase, Samwel ;

Kahabuka, Catherine ;

Mtove, George ;

Nadjm, Behzad ;

Deen, Jacqueline ;

Amumpaire, Juliet Mwanga ;

Nansumba, Margaret ;

Karema, Corine ;

Umulisa, Noella ;

Uwimana, Aline ;

Mokuolu, Olugbenga A. ;

Adedoyin, Olanrewaju T. ;

Johnson, Wahab B. R. ;

Tshefu, Antoinette K. ;

Onyamboko, Marie A. ;

Sakulthaew, Tharisara ;

Ngum, Wirichada Pan ;

Silamut, Kamolrat ;

Stepniewska, Kasia ;

Woodrow, Charles J. ;

Bethell, Delia ;

Wills, Bridget ;

Oneko, Martina ;

Peto, Tim E. ;

von Seidlein, Lorenz ;

Day, Nicholas P. J. ;

White, Nicholas J. .

LANCET, 2010, 376 (9753) :1647-1657

[5] Genetic diversity and deletion of Plasmodium falciparum histidine-rich protein 2 and 3: a threat to diagnosis of P. falciparum malaria [J].

Gendrot, M. ;

Fawaz, R. ;

Dormoi, J. ;

Madamet, M. ;

Pradines, B. .

CLINICAL MICROBIOLOGY AND INFECTION, 2019, 25 (05) :580-585

[6] Assessment of the prozone effect in malaria rapid diagnostic tests [J].

Gillet, Philippe ;

Mori, Marcella ;

Van Esbroeck, Marjan ;

Van den Ende, Jef ;

Jacobs, Jan .

MALARIA JOURNAL, 2009, 8

[7]

Khatamazas E., 2021, DEUT ARZTEBLATT, V118

[8] Severe malaria in Europe: an 8-year multi-centre observational study [J].

Kurth, Florian ;

Develoux, Michel ;

Mechain, Matthieu ;

Malvy, Denis ;

Clerinx, Jan ;

Antinori, Spinello ;

Gjorup, Ida E. ;

Gascon, Joaquim ;

Morch, Kristine ;

Nicastri, Emanuele ;

Ramharter, Michael ;

Bartoloni, Alessandro ;

Visser, Leo ;

Rolling, Thierry ;

Zanger, Philipp ;

Calleri, Guido ;

Salas-Coronas, Joaquin ;

Nielsen, Henrik ;

Just-Nuebling, Gudrun ;

Neumayr, Andreas ;

Hachfeld, Anna ;

Schmid, Matthias L. ;

Antonini, Pietro ;

Lingscheid, Tilman ;

Kern, Peter ;

Kapaun, Annette ;

da Cunha, Jose Saraiva ;

Pongratz, Peter ;

Soriano-Arandes, Antoni ;

Schunk, Mirjam ;

Suttorp, Norbert ;

Hatz, Christoph ;

Zoller, Thomas .

MALARIA JOURNAL, 2017, 16 :1-11

[9] Intravenous Artesunate Reduces Parasite Clearance Time, Duration of Intensive Care, and Hospital Treatment in Patients With Severe Malaria in Europe: The TropNet Severe Malaria Study [J].

Kurth, Florian ;

Develoux, Michel ;

Mechain, Matthieu ;

Clerinx, Jan ;

Antinori, Spinello ;

Gjorup, Ida E. ;

Gascon, Joaquim ;

Morch, Kristine ;

Nicastri, Emanuele ;

Ramharter, Michael ;

Bartoloni, Alessandro ;

Visser, Leo ;

Rolling, Thierry ;

Zanger, Philipp ;

Calleri, Guido ;

Salas-Coronas, Joaquin ;

Nielsen, Henrik ;

Just-Nuebling, Gudrun ;

Neumayr, Andreas ;

Hachfeld, Anna ;

Schmid, Matthias L. ;

Antonini, Pietro ;

Pongratz, Peter ;

Kern, Peter ;

da Cunha, Jose Saraiva ;

Soriano-Arandes, Antoni ;

Schunk, Mirjam ;

Suttorp, Norbert ;

Hatz, Christoph ;

Zoller, Thomas .

CLINICAL INFECTIOUS DISEASES, 2015, 61 (09) :1441-1444

[10] Quantification of malaria antigens PfHRP2 and pLDH by quantitative suspension array technology in whole blood, dried blood spot and plasma [J].

Martianez-Vendrell, Xavier ;

Jimenez, Alfons ;

Vasquez, Ana ;

Campillo, Ana ;

Incardona, Sandra ;

Gonzalez, Raquel ;

Gamboa, Dionicia ;

Torres, Katherine ;

Oyibo, Wellington ;

Faye, Babacar ;

Macete, Eusebio ;

Menendez, Clara ;

Ding, Xavier C. ;

Mayor, Alfredo .

MALARIA JOURNAL, 2020, 19 (01)

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