Secondary amines immobilized inside magnetic mesoporous materials as a recyclable basic and oxidative heterogeneous nanocatalyst for the synthesis of trisubstituted pyrimidine derivatives

被引：11

作者：

Aryan, Reza ^{[1
]}

Beyzaei, Hamid ^{[1
]}

Nojavan, Masoomeh ^{[1
]}

Dianatipour, Tahereh ^{[1
]}

机构：

[1] Univ Zabol, Dept Chem, Fac Sci, POB 9861335856, Zabol, Iran

来源：

RESEARCH ON CHEMICAL INTERMEDIATES | 2016年 / 42卷 / 05期

关键词：

Magnetic mesoporous material; Hybrid organic-inorganic catalyst; Piperazine; Pyrimidine derivatives; Multicomponent reaction; METAL-ORGANIC FRAMEWORK; ALPHA-FE2O3-MCM-41; NANOPARTICLES; STABILITY; CATALYSTS; EFFICIENT; CO2;

D O I：

10.1007/s11164-015-2284-y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel magnetic MCM-41 nanocomposite-based catalyst is reported for the first time in the multicomponent synthesis of trisubstituted pyrimidines in which piperazine is immobilized inside the mesochannels of magnetic MCM-41 as an organic base (alpha-Fe2O3-MCM-41-piperazine). This nanocatalyst was thoroughly characterized by various techniques such as FT-IR, XRD, SEM, TEM, EDX and N-2-adsorption isotherms. Very uniform dispersion and ordered mesopores of alpha-Fe2O3-MCM-41 causes piperazine molecules to be distributed very finely on the internal surface of the pores, resulting in a very useful and robust magnetically recyclable amine-based heterogeneous nanocatalyst. This catalytic system showed remarkable activity in the solvent-free synthesis of 2,4,6-trisubstituted pyrimidine derivatives.

引用

页码：4417 / 4431

页数：15

共 51 条

[1] Solid support synthesis of 6-aryl-2-substituted pyrimidin-4-yl phenols as anti-infective agents [J].