The Erlangen Fitness Osteoporosis Prevention Study: A controlled exercise trial in early postmenopausal women with low bone density - First-year results

被引:57
作者
Kemmler, W
Engelke, K
Weineck, J
Hensen, J
Kalender, WA
机构
[1] Univ Erlangen Nurnberg, Inst Med Phys, D-91054 Erlangen, Germany
[2] Univ Erlangen Nurnberg, Inst Sport Sci, D-91054 Erlangen, Germany
[3] Klinikum Hannover Nordstadt, Med Klin 1, Hannover, Germany
来源
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION | 2003年 / 84卷 / 05期
关键词
bone density; exercise; osteoporosis; postmenopause; physical endurance; rehabilitation; women;
D O I
10.1016/S0003-9993(03)04908-0
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Objective: To investigate the effect of a 2-year vigorous, combined high-impact, strength, and endurance training program on bone mineral density (BMD) determined by dual-energy x-ray absorptiometry (DXA), quantitative computed tomography (QCT), and ultrasound in early postmenopausal women with osteopenia. Design: Nonrandomized controlled trial, reporting 1-year data. Setting: Community. Participants: Early postmenopausal (1-8y postmenopausal) osteopenic women (DXA T score at lumbar spine or total hip between -1 and -2.5 standard deviations). The exercise group (n=59; mean age, 55.1 +/- 3.4y) and control group (n = 41; mean age, 55.9 +/- 3.1 y) were recruited from community registers. Intervention: Fourteen months of exercise training, with 2 joint sessions and 2 additional home training sessions. Exercise and control groups were supplemented individually with calcium and cholecalciferol up to 1500mg of calcium and 500IU of vitamin D per day. Main Outcome Measures: BMD at the lumbar spine and total hip measured by DXA, isometric maximum strength, and maximal oxygen consumption (Vo(2)max) during a stepwise running test to exhaustion. Results: Bone density increased significantly at the lumbar Spine for the exercise group (1.3%, P<.001) and decreased in the control group (-1.2%, P<.01). Differences at the total hip (-0.3%, not significant vs -0.8%, P<.05) and the femoral neck (-0.8%, P<.05 vs -1.8%, P<.001) were nonsignificant. Changes in isometric maximum strength were significant for each region (grip strength, trunk flexors and extensors, hip flexors, leg adductors and abductors, arm flexors and extensors) in the exercise group (11%-39%) compared with nonrelevant changes (-1.1% to 3.9%) in the control group. Between-group differences were significant (P<.01-.001) for all strength parameters. VO(2)max increased significantly by 11% (P<.001) in the exercise group but decreased in the control group by 4% (P<.05) while showing significant between-group differences. Conclusion: High-intensity exercise training can have a positive, influence, on bone density in early postmenopausal osteopenic women.
引用
收藏
页码:673 / 682
页数:10
相关论文
共 53 条
[1]  
[Anonymous], 1998, Dtsch Z Sportmed
[2]   Tomographical description of tennis-loaded radius: reciprocal relation between bone size and volumetric BMD [J].
Ashizawa, N ;
Nonaka, K ;
Michikami, S ;
Mizuki, T ;
Amagai, H ;
Tokuyama, K ;
Suzuki, M .
JOURNAL OF APPLIED PHYSIOLOGY, 1999, 86 (04) :1347-1351
[3]   EXERCISE IN PRIMARY PREVENTION OF OSTEOPOROSIS IN WOMEN [J].
BASSEY, EJ .
ANNALS OF THE RHEUMATIC DISEASES, 1995, 54 (11) :861-862
[4]   INCREASE IN FEMORAL BONE-DENSITY IN YOUNG-WOMEN FOLLOWING HIGH-IMPACT EXERCISE [J].
BASSEY, EJ ;
RAMSDALE, SJ .
OSTEOPOROSIS INTERNATIONAL, 1994, 4 (02) :72-75
[5]   Pre- and postmenopausal women have different bone mineral density responses to the same high-impact exercise [J].
Bassey, EJ ;
Rothwell, MC ;
Littlewood, JJ ;
Pye, DW .
JOURNAL OF BONE AND MINERAL RESEARCH, 1998, 13 (12) :1805-1813
[6]   Musculoskeletal responses to high- and low-intensity resistance training in early postmenopausal women [J].
Bemben, DA ;
Fetters, NL ;
Bemben, MG ;
Nabavi, N ;
Koh, ET .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2000, 32 (11) :1949-1957
[7]   EFFECTS OF EXERCISE TRAINING ON BONE-DENSITY IN OLDER MEN AND WOMEN [J].
BLUMENTHAL, JA ;
EMERY, CF ;
MADDEN, DJ ;
SCHNIEBOLK, S ;
RIDDLE, MW ;
COBB, FR ;
HIGGINBOTHAM, M ;
COLEMAN, RE .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1991, 39 (11) :1065-1070
[8]   Impact of a 12-month exercise program on the physical and psychological health of osteopenic women [J].
Bravo, G ;
Gauthier, P ;
Roy, PM ;
Payette, H ;
Gaulin, P ;
Hervey, M ;
Peloquin, L ;
Dubois, MF .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1996, 44 (07) :756-762
[9]  
CHAE A, 1994, REGULATIONS REPAIRME
[10]   EFFECT OF 2 RANDOMIZED EXERCISE PROGRAMS ON BONE MASS OF HEALTHY POSTMENOPAUSAL WOMEN [J].
CHOW, R ;
HARRISON, JE ;
NOTARIUS, C .
BMJ-BRITISH MEDICAL JOURNAL, 1987, 295 (6611) :1441-1444