Role of Decidual Natural Killer Cells at the Maternal-Fetal Interface during Pregnancy

被引：6
作者：
Yang, Shao-Liang [1 ]
Wang, Hai-Yan [2 ]
Li, Da-Jin [1 ]
Li, Ming-Qing [1 ,3 ]
机构：
[1] Fudan Univ, Hosp Obstet & Gynecol, Shanghai Inst Planned Parenthood Res, NHC Key Lab Reprod Regulat, 1326 Pingliang Rd, Shanghai 200080, Peoples R China
[2] Fudan Univ, Hosp Obstet & Gynecol, Dept Gynecol Integrated Tradit Chinese & Western, 128 Shenyang Rd, Shanghai 200011, Peoples R China
[3] Fudan Univ, Shanghai Key Lab Female Reprod Endocrine Related, Shanghai 200011, Peoples R China
来源：
REPRODUCTIVE AND DEVELOPMENTAL MEDICINE | 2019年 / 3卷 / 03期
关键词：
Decidual Natural Killer Cells; Maternal-Fetal Immune Tolerance; Vascular Remodeling; NK CELLS; IMMUNE CELLS; UTERINE; PHENOTYPE; MIGRATION; NEUTROPHILS; ACTIVATION; EXPRESSION; TOLERANCE; SURVIVAL;
D O I：
10.4103/2096-2924.268161
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Pregnancy is a complicated process with intricate cell-to-cell crosstalk and immune regulation. Decidual natural killer (NK) cells account for 50%-70% of decidual immune cells in early pregnancy, suggesting that they play important roles in various events, such as embryo implantation and vascular remodeling. Many studies have shown that decidual NK cells interact with other cells either through direct contact or the secretion factors such as cytokines and chemokines. Hence, this review aimed to present the phenotypic characteristics, classification, and functions of decidual NK cells at the maternal-fetal interface during pregnancy.
引用
收藏
页码：165 / 169
页数：5
相关论文
共 45 条
[1]   Role of placenta growth factor (PIGF) in human extravillous trophoblast proliferation, migration and invasiveness [J].
Athanassiades, A ;
Lala, PK .
PLACENTA, 1998, 19 (07) :465-473
[2]   Tumor necrosis factor-α inhibits trophoblast migration through elevation of plasminogen activator inhibitor-1 in first-trimester villous explant cultures [J].
Bauer, S ;
Pollheimer, J ;
Hartmann, J ;
Husslein, P ;
Aplin, JD ;
Knöfler, M .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (02) :812-822
[3]   Immune cells in the placental bed [J].
Bulmer, Judith N. ;
Williams, Paula J. ;
Lash, Gendie E. .
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, 2010, 54 (2-3) :281-294
[4]   Conversion of Peripheral Blood NK Cells to a Decidual NK-like Phenotype by a Cocktail of Defined Factors [J].
Cerdeira, Ana Sofia ;
Rajakumar, Augustine ;
Royle, Caroline M. ;
Lo, Agnes ;
Husain, Zaheed ;
Thadhani, Ravi I. ;
Sukhatme, Vikas P. ;
Karumanchi, S. Ananth ;
Kopcow, Hernan D. .
JOURNAL OF IMMUNOLOGY, 2013, 190 (08) :3939-3948
[5]   Maternal KIR and fetal HLA-C: a fine balance [J].
Chazara, Olympe ;
Xiong, Shiqiu ;
Moffett, Ashley .
JOURNAL OF LEUKOCYTE BIOLOGY, 2011, 90 (04) :703-716
[6]   The defensive alliance between neutrophils and NK cells as a novel arm of innate immunity [J].
Costantini, Claudio ;
Cassatella, Marco A. .
JOURNAL OF LEUKOCYTE BIOLOGY, 2011, 89 (02) :221-233
[7]   Neutrophil activation and survival are modulated by interaction with NK cells [J].
Costantini, Claudio ;
Micheletti, Alessandra ;
Calzetti, Federica ;
Perbellini, Omar ;
Pizzolo, Giovanni ;
Cassatella, Marco A. .
INTERNATIONAL IMMUNOLOGY, 2010, 22 (10) :827-838
[8]   Decidual spiral artery remodelling begins before cellular interaction with cytotrophoblasts [J].
Craven, CM ;
Morgan, T ;
Ward, K .
PLACENTA, 1998, 19 (04) :241-252
[9]   Group 3 innate lymphoid cells regulate neutrophil migration and function in human decidua [J].
Croxatto, D. ;
Micheletti, A. ;
Montaldo, E. ;
Orecchia, P. ;
Loiacono, F. ;
Canegallo, F. ;
Calzetti, F. ;
Fulcheri, E. ;
Munari, E. ;
Zamo, A. ;
Venturini, P. L. ;
Moretta, L. ;
Cassatella, M. A. ;
Mingari, M. C. ;
Vacca, P. .
MUCOSAL IMMUNOLOGY, 2016, 9 (06) :1372-1383
[10]   Role of Interleukin 8 in Uterine Natural Killer Cell Regulation of Extravillous Trophoblast Cell Invasion [J].
De Oliveira, L. G. ;
Lash, G. E. ;
Murray-Dunning, C. ;
Bulmer, J. N. ;
Innes, B. A. ;
Searle, R. F. ;
Sass, N. ;
Robson, S. C. .
PLACENTA, 2010, 31 (07) :595-601
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