Analysis of a two-dimensional triply haptotactic model with a fusogenic oncolytic virus and syncytia

被引:4
作者
Ren, Guoqiang [1 ,2 ]
Wei, Jinlong [3 ]
机构
[1] Huazhong Univ Sci & Technol, Sch Math & Stat, Wuhan 430074, Peoples R China
[2] Huazhong Univ Sci & Technol, Hubei Key Lab Engn Modeling & Sci Comp, Wuhan 430074, Peoples R China
[3] Zhongnan Univ Econ & Law, Sch Stat & Math, Wuhan 430073, Peoples R China
来源
ZEITSCHRIFT FUR ANGEWANDTE MATHEMATIK UND PHYSIK | 2021年 / 72卷 / 04期
关键词
Haptotaxis; Global solution; Oncolytic virotherapy; Syncytia cancer cells; REPULSION CHEMOTAXIS MODEL; GLOBAL WEAK SOLUTIONS; ASYMPTOTIC-BEHAVIOR; BLOW-UP; LOGISTIC SOURCE; STOKES SYSTEM; BOUNDEDNESS; EXISTENCE; STABILIZATION; DIFFUSION;
D O I
10.1007/s00033-021-01572-0
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
In this paper, we concerned with a haptotaxis system proposed as a model for fusogenic oncolytic virotherapy and syncytia, accounting for interaction between uninfected cancer cells, infected cancer cells, syncytia cancer cells, extracellular matrix and oncolytic virus. We present the global classical solution in two-dimensional bounded domains under appropriate regularity assumptions on the initial data.
引用
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页数:23
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