Characterization and Detection of Food Allergens Using High-Resolution Mass Spectrometry: Current Status and Future Perspective

被引:19
作者
Braecker, Julia [1 ]
Brockmeyer, Jens [1 ]
机构
[1] Univ Stuttgart, Dept Food Chem, Inst Biochem & Tech Biochem, Allmandring 5b, D-70569 Stuttgart, Germany
关键词
allergy; food safety; peptidomics; targeted proteomics; NUT ALLERGENS; BIRTH COHORT; EXPERT PANEL; QUANTIFICATION; IDENTIFICATION; MULTIMETHOD; PROTEOMICS; DIAGNOSIS; PEPTIDES;
D O I
10.1021/acs.jafc.8b02265
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
Allergic reactions to food are among the major food safety concerns in industrialized countries, and it is estimated that approximately 5% of the population suffers from immunoglobulin-E-mediated food allergy. High-resolution mass spectrometry has become one of the most important techniques for the molecular characterization of allergens, including structural modification, degradation in the gastrointestinal environment, or identification of suitable marker peptides for the development of novel analytical approaches, in the past decade. This perspective aims to briefly summarize the current situation and discuss future developments.
引用
收藏
页码:8935 / 8940
页数:6
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