Menage a Trio during BMP-Mediated Retrograde Signaling at the NMJ

被引：14

作者：

Fuentes-Medel, Yuly ^{[1
]}

Budnik, Vivian ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Neurobiol, Worcester, MA 01605 USA

来源：

NEURON | 2010年 / 66卷 / 04期

关键词：

DROSOPHILA NEUROMUSCULAR-JUNCTION; REGULATES SYNAPTIC GROWTH; II RECEPTOR; MAD;

D O I：

10.1016/j.neuron.2010.05.016

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In flies, retrograde BMP signaling is an important mechanism by which postsynaptic cells regulate the structure and function of presynaptic terminals, ostensibly through changes in gene expression. Transcriptional targets, however, have remained mysterious. In this issue of Neuron, Haghighi and colleagues begin to unravel this puzzle by identifying the cytoskeletal regulator Trio.

引用

页码：473 / 475

页数：3

共 14 条

[1] wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila [J].

Aberle, H ;

Haghighi, AP ;

Fetter, RD ;

McCabe, BD ;

Magalhaes, TR ;

Goodman, CS .

NEURON, 2002, 33 (04) :545-558

[2] Retrograde BMP Signaling Controls Synaptic Growth at the NMJ by Regulating Trio Expression in Motor Neurons [J].

Ball, Robin W. ;

Warren-Paquin, Maude ;

Tsurudome, Kazuya ;

Liao, Edward H. ;

Elazzouzi, Fatima ;

Cavanagh, Chelsea ;

An, Beum-Soo ;

Wang, Tian-Tian ;

White, John H. ;

Haghighi, A. Pejmun .

NEURON, 2010, 66 (04) :536-549

[3] Homeostatic control of neural activity: From phenomenology to molecular design [J].

Davis, Graeme W. .

ANNUAL REVIEW OF NEUROSCIENCE, 2006, 29 :307-323

[4] Postsynaptic mad signaling at the Drosophila neuromuscular junction [J].

Dudu, V ;

Bittig, T ;

Entchev, E ;

Kicheva, A ;

Jülicher, F ;

González-Gaitán, M .

CURRENT BIOLOGY, 2006, 16 (07) :625-635

[5]

ELLIS JE, 2010, DEV BIOL, V24, P24

[6] The BMP ligand Gbb gates the expression of synaptic horneostasis independent of synaptic growth control [J].

Goold, Carleton P. ;

Davis, Graeme W. .

NEURON, 2007, 56 (01) :109-123

[7] Drosophila liprin-α and the receptor phosphatase Dlar control synapse morphogenesis [J].

Kaufmann, N ;

DeProto, J ;

Ranjan, R ;

Wan, H ;

Van Vactor, D .

NEURON, 2002, 34 (01) :27-38

[8] WNTs tune up the neuromuscular junction [J].

Korkut, Ceren ;

Budnik, Vivian .

NATURE REVIEWS NEUROSCIENCE, 2009, 10 (09) :627-634

[9] The Drosophila BMP type II receptor wishful thinking regulates neuromuscular synapse morphology and function [J].

Marqués, G ;

Bao, H ;

Haerry, TE ;

Shimell, MJ ;

Duchek, P ;

Zhang, B ;

O'Connor, MB .

NEURON, 2002, 33 (04) :529-543

[10] The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction [J].

McCabe, BD ;

Marqués, G ;

Haghighi, AP ;

Fetter, RD ;

Crotty, ML ;

Haerry, TE ;

Goodman, CS ;

O'Connor, MB .

NEURON, 2003, 39 (02) :241-254

← 1 2 →