Chemical constituents of the leaves of rabbiteye blueberry (Vaccinium ashei) and characterisation of polymeric proanthocyanidins containing phenylpropanoid units and A-type linkages

被引：80

作者：

Matsuo, Yosuke ^{[1
]}

Fujita, Yusuke ^{[1
]}

Ohnishi, Sachiko ^{[1
]}

Tanaka, Takashi ^{[1
]}

Hirabaru, Hideaki ^{[2
]}

Kai, Takanori ^{[2
]}

Sakaida, Hiroshi ^{[2
]}

Nishizono, Shoko ^{[3
]}

Kouno, Isao ^{[1
]}

机构：

[1] Nagasaki Univ, Grad Sch Biomed Sci, Dept Nat Prod Chem, Nagasaki 8528521, Japan

[2] Unkai Shuzo Co Ltd, Res Inst, Miyazaki 8801303, Japan

[3] Miyazaki Univ, Cooperat Res Ctr, Miyazaki 8892192, Japan

来源：

FOOD CHEMISTRY | 2010年 / 121卷 / 04期

关键词：

Blueberry; Vaccinium ashei; Polyphenol; Proanthocyanidin; Catechin; Cinchonain; THUNBERGIANUM MIQ NAKAI; FLAVONOL GLYCOSIDES; READE LEAVES; LEAF EXTRACT; IN-VITRO; TANNINS; FRUITS; RATS; PROCYANIDINS; CRANBERRIES;

D O I：

10.1016/j.foodchem.2010.01.052

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Chemical constituents of the leaves of rabbiteye blueberry (Vaccinium ashei READE) were investigated in detail. The major phenolic components were caffeoyl quinic acids, flavonol glycosides, flavan-3-ols and proanthocyanidins. Catechins and proanthocyanidins having additional phenylpropanoid units, such as cinchonains, kandelins and mururins, characterised the polyphenols of this plant. Among them, vaccinin A, an isomer of mururin A, was found to be a new compound, and the structure was characterised by spectroscopic methods. The most abundant polyphenols (11.3% of freeze-dried leaves) were oligomeric proanthocyanidins. Thiol degradation with mercaptoethanol indicated that the polymer was constituted of (+)-catechin and (-)-epicatechin as the terminal units and (-)-epicatechin, procyanidin A-2, and cinchonains Ia and Ib as the extension units. Mass spectral analysis suggested the presence of at least dodecamers with A-type linkages and phenylpropanoid moieties. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：1073 / 1079

页数：7

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