Preterm delivery and exposure to active and passive smoking during pregnancy: a case-control study from Italy

被引:79
作者
Fantuzzi, Guglielmina
Aggazzotti, Gabriella
Righi, Elena
Facchinetti, Fabio
Bertucci, Emma
Kanitz, Stefano
Barbone, Fabio
Sansebastiano, Giuliano
Battaglia, Mario Alberto
Leoni, Valerio
Fabiani, Leila
Triassi, Maria
Sciacca, Salvatore
机构
[1] Univ Modena & Reggio Emilia, Dept Publ Hlth Sci, Modena, Italy
[2] Dipartimento Sci Sanita Pubbl, I-41100 Modena, Italy
[3] Univ Genoa, Dept Hlth Sci, Genoa, Italy
[4] Univ Udine, Dept Publ Hlth Sci, I-33100 Udine, Italy
[5] Univ Parma, Dept Expt & Clin Med & Pathol, I-43100 Parma, Italy
[6] Univ Roma La Sapienza, Hyg Inst G Sanarelli, Rome, Italy
[7] Univ Aquila, Dept Internal Med & Publ Hlth, I-67100 Laquila, Italy
[8] Univ Naples Federico II, Dept Prevent Med Sci, Unit Hyg, Naples, Italy
[9] Univ Catania, Dept Biomed Sci, Catania, Italy
关键词
preterm delivery; maternal smoking; environmental tobacco smoke; ENVIRONMENTAL TOBACCO-SMOKE; WOMEN; BIRTH; ASSOCIATION; COTININE; SERUM; RISK;
D O I
10.1111/j.1365-3016.2007.00815.x
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The aim of this study was to assess the relationship between preterm/early preterm delivery and active smoking as well as environmental tobacco smoke (ETS) exposure in a sample of pregnant Italian women. A case-control study was conducted in nine cities in Italy between October 1999 and September 2000. Cases of preterm birth were singleton babies born before the 37th gestational week; babies born before the 35th gestational week were considered early preterm births. Controls were babies with gestational ages >= 37th week. A total of 299 preterm cases (including 105 early preterm) and 855 controls were analysed. A self-administered questionnaire was used to assess active smoking and ETS exposure, as well as potential confounders. Multivariable logistic regression analysis showed a relationship between active smoking during pregnancy and preterm/early preterm delivery [adjusted ORs: 1.53; 95% CI 1.05, 2.21 and 2.00; 95% CI 1.16, 3.45, respectively]. A dose-response relationship was found for the number of cigarettes smoked daily. The adjusted ORs were 1.54 and 1.69 for preterm babies and 1.90 and 2.46 for early preterm babies for 1-10 and > 10 cigarettes/day respectively. ETS exposure was associated with early preterm delivery [adjusted OR 1.56; 95% CI 0.99, 2.46] with a dose-response relationship with the number of smokers in the home. Smoking during pregnancy was strongly associated with preterm delivery with a dose-response effect. ETS exposure in non-smoking women was associated only with early preterm delivery.
引用
收藏
页码:194 / 200
页数:7
相关论文
共 23 条
[1]  
Aggazzotti Gabriella, 2004, Journal of Water and Health, V2, P233
[2]   Preterm birth among African American and white women: a multilevel analysis of socioeconomic characteristics and cigarette smoking [J].
Ahern, J ;
Pickett, KE ;
Selvin, S ;
Abrams, B .
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 2003, 57 (08) :606-611
[3]  
Albizu L, 2000, An Sist Sanit Navar, V23, P337
[4]  
[Anonymous], 2004, HLTH CONS SMOK REP S
[5]   Assessing the exposure of pregnant women to drinking water disinfection byproducts [J].
Barbone, F ;
Valent, F ;
Brussi, V ;
Tomasella, L ;
Triassi, M ;
Di Lieto, A ;
Scognamiglio, G ;
Righi, E ;
Fantuzzi, G ;
Casolari, L ;
Aggazzotti, G .
EPIDEMIOLOGY, 2002, 13 (05) :540-544
[6]   The complex relationship between smoking in pregnancy and very preterm delivery.: Results of the Epipage study [J].
Burguet, A ;
Kaminski, M ;
Abraham-Lerat, L ;
Schaal, JP ;
Cambonie, G ;
Fresson, J ;
Grandjean, H ;
Truffert, P ;
Marpeau, L ;
Voyer, M ;
Rozé, JC ;
Treisser, A ;
Larroque, B .
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2004, 111 (03) :258-265
[7]  
*CAL EPA, 2004, HLTH EFF ASS ETS
[8]   Variation of serum and urine cotinine in passive and active smokers and applicability in preconceptional smoking cessation counseling [J].
de Weerd, S ;
Thomas, CMG ;
Kuster, JETG ;
Cikot, RJLM ;
Steegers, EAP .
ENVIRONMENTAL RESEARCH, 2002, 90 (02) :119-124
[9]   Exposure to environmental tobacco smoke in pregnant women: The association between self-report and serum cotinine [J].
DeLorenze, GN ;
Kharrazi, M ;
Kaufman, FL ;
Eskenazi, B ;
Bernert, JT .
ENVIRONMENTAL RESEARCH, 2002, 90 (01) :21-32
[10]  
*DOXA, FUM IT 2003