Characterization of Mycophenolate Mofetil Gastrointestinal Toxicity and Risk Factors for Severe Disease and Poor Prognosis

被引：5

作者：

Bhattacharya, Sumona ^{[1
,2
]}

Stoleru, Gianna ^{[3
]}

Patel, Preet ^{[3
]}

Abutaleb, Ameer ^{[2
]}

Stashek, Kristen ^{[4
]}

Cross, Raymond K. ^{[2
]}

机构：

[1] NIDDK, Digest Dis Branch, NIH, Bethesda, MD 20892 USA

[2] Univ Maryland, Sch Med, Dept Med, Div Gastroenterol & Hepatol, Baltimore, MD 21201 USA

[3] Univ Maryland, Dept Med, Med Ctr, Baltimore, MD 21201 USA

[4] Univ Maryland, Sch Med, Dept Pathol, Baltimore, MD 21201 USA

来源：

INFLAMMATORY BOWEL DISEASES | 2022年 / 28卷 / 05期

关键词：

mycophenolate mofetil; mycophenolate mofetil colitis; mycophenolate mofetil gastrointestinal toxicity; COLITIS; FEATURES; SPECTRUM;

D O I：

10.1093/ibd/izab254

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Lay Summary Authors performed a chart review to identify cases of mycophenolate mofetil gastrointestinal toxicity at our institution. In this cohort, friability was associated with severe disease; and nausea and erythema were associated with poor prognosis.

引用

页码：811 / 814

页数：4

共 10 条

[1] Calmet FH, 2015, ANN GASTROENTEROL, V28, P366
[2] Microscopic features associated with mycophenolate mofetil in gastric and colonic biopsies
Coyne, John D.
Campbell, Fiona
[J]. HISTOPATHOLOGY, 2012, 61 (05) : 993 - 997
[3] Crohn's-like changes in the colon due to mycophenolate?
Dalle, IJ
Maes, BD
Geboes, KP
Lemahieu, W
Geboes, K
[J]. COLORECTAL DISEASE, 2005, 7 (01) : 27 - 34
[4] Clinicopathologic features and outcome of mycophenolate-induced colitis in renal transplant recipients
de Andrade, Luis Gustavo M.
Rodrigues, Maria Aparecida M.
Romeiro, Fernando G.
Garcia, Paula D.
Contti, Mariana M.
de Carvalho, Maria Fernanda C.
[J]. CLINICAL TRANSPLANTATION, 2014, 28 (11) : 1244 - 1248
[5] Histological spectrum of mycophenolate mofetil-related colitis: association with apoptosis
Liapis, George
Boletis, John
Skalioti, Chrysanthi
Bamias, George
Tsimaratou, Katerina
Patsouris, Efstratios
Delladetsima, Ioanna
[J]. HISTOPATHOLOGY, 2013, 63 (05) : 649 - 658
[6] Histologic features of mycophenolate mofetil-related colitis: A graft-versus-host disease-like pattern
Papadimitriou, JC
Cangro, CB
Lustberg, A
Khaled, A
Nogueira, J
Wiland, A
Ramos, E
Klassen, DK
Drachenberg, CB
[J]. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2003, 11 (04) : 295 - 302
[7] Risk factors that influence the incidence and severity of MMF adverse events in renal transplant patients:: Relationship with corticosteroid dosage, renal function, sex, and patient age
Puig, JM
Fernández-Crespo, P
Lloveras, J
Mir, M
Iñigo, V
Manresa, JM
Masramón, J
[J]. TRANSPLANTATION PROCEEDINGS, 1999, 31 (06) : 2270 - 2271
[8] Riskalla MM, 2003, J RHEUMATOL, V30, P1508
[9] COATED ORAL 5-AMINOSALICYLIC ACID THERAPY FOR MILDLY TO MODERATELY ACTIVE ULCERATIVE-COLITIS - A RANDOMIZED STUDY
SCHROEDER, KW
TREMAINE, WJ
ILSTRUP, DM
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (26) : 1625 - 1629
[10] Spectrum of histologic changes in colonic biopsies in patients treated with mycophenolate mofetil
Selbst, Megan K.
Ahrens, William A.
Robert, Marie E.
Friedman, Amy
Proctor, Deborah D.
Jain, Dhanpat
[J]. MODERN PATHOLOGY, 2009, 22 (06) : 737 - 743

← 1 →