The Association between Left Ventricular Diastolic Dysfunction and Increased Aortic Stiffness Can Be Explained by Possible Neurohumoral Mechanisms

被引:2
|
作者
Surucu, Huseyin [1 ]
Tatli, Ersan [2 ]
Boz, Hakki [3 ]
Meric, Mehmet [4 ]
机构
[1] Private Avcilar Anadolu Hosp, Dept Cardiol, Istanbul, Turkey
[2] Trakya Univ, Dept Cardiol, Sch Med, Edirne, Turkey
[3] Private Avcilar Anadolu Hosp, Dept Internal Med, Istanbul, Turkey
[4] JFK Hosp, Dept Cardiol, Istanbul, Turkey
来源
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES | 2010年 / 27卷 / 03期
关键词
left ventricular diastolic dysfunction; increased aortic stiffness; CORONARY-ARTERY-DISEASE; PRESSURE-DIAMETER RELATION; PULSE-WAVE VELOCITY; ELASTIC PROPERTIES; HEART-FAILURE; HYPERTENSIVE PATIENTS; CARDIOVASCULAR RISK; DIABETES-MELLITUS; ASCENDING AORTA; DISTENSIBILITY;
D O I
10.1111/j.1540-8175.2009.01017.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: In our study, we tried to find an answer to the question "How could the association between left ventricular diastolic dysfunction (LVDDF) and increased aortic stiffness (IAS) be explained?" Methods: Cases without coronary artery disease (CAD) were divided into three groups according to their left ventricular (LV) inflow patterns and their LV basal-lateral annulus pulsed-wave tissue Doppler imaging (pw-TDI). Group 1 (n = 38) represented the normal LV inflow pattern while Group 2 (n = 54) represented impaired LV relaxation and Group 3 (n = 18) represented pseudonormalization. Aortic diameters were measured by using M-mode at a level that is 3 cm above the aortic valve. Aortic strain (AS) and aortic distensibility (AD) were calculated by using aortic diameters and pulse pressure. Results: In Group 3, AS was lower compared to Groups 1 and 2 (respectively P < 0.001, P = 0.040). AS was also lower in Group 2 compared to Group 1 (P = 0.012). AD was higher in Group 1 compared to Groups 2 and 3 (respectively P = 0.01, P < 0.001). Early diastolic velocity of aortic pw-TDI was higher in normal LV inflow compared to Groups 2 and 3 (respectively P = 0.022, P = 0.050). Unfortunately, none of echocardiographic parameters that evaluate LV and aortic functions together (stroke volume, pulse pressure/stroke volume, pulse pressure/stroke volume index) were different among the groups. Conclusion: The results of our study clearly showed the association between LVDDF and IAS in cases without CAD. Additionally, it was concluded that this togetherness could be explained not by hemodynamic factors but by possible neurohumeral mechanisms. (Echocardiography 2010;27:275-281).
引用
收藏
页码:275 / 281
页数:7
相关论文
共 50 条
  • [1] Association Between Endothelial Dysfunction and Left Ventricular Diastolic Stiffness
    Takei, Yasuyoshi
    Tomiyama, Hirofumi
    Higashi, Yukihito
    Yamashina, Akira
    Chikamori, Taishiro
    CIRCULATION JOURNAL, 2023, 87 (09) : 1203 - 1211
  • [2] Association of Increased Arterial Stiffness and P Wave Dispersion with Left Ventricular Diastolic Dysfunction
    Tsai, Wei-Chung
    Lee, Kun-Tai
    Kuo, Hsuan-Fu
    Tang, Wei-Hua
    Jhuo, Shih-Jie
    Chu, Chih-Sheng
    Lin, Tsung-Hsien
    Hsu, Po-Chao
    Lin, Ming-Yen
    Lin, Feng-Hsien
    Su, Ho-Ming
    Voon, Wen-Chol
    Lai, Wen-Ter
    Sheu, Sheng-Hsiung
    INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, 2013, 10 (11): : 1437 - 1444
  • [3] Aortic stiffness is an independent determinant of left ventricular diastolic dysfunction in metabolic syndrome patients
    Solovjova, Svetlana
    Ryliskyte, Ligita
    Celutkiene, Jelena
    Badariene, Jolita
    Navickas, Rokas
    Puronaite, Roma
    Bieliauskaite, Gryte
    Skiauteryte, Egle
    Lisaite, Giedre
    Laucevicius, Aleksandras
    BLOOD PRESSURE, 2016, 25 (01) : 11 - 20
  • [4] Association of Arterial Stiffness and Electrocardiography-Determined Left Ventricular Hypertrophy with Left Ventricular Diastolic Dysfunction
    Hsu, Po-Chao
    Tsai, Wei-Chung
    Lin, Tsung-Hsien
    Su, Ho-Ming
    Voon, Wen-Chol
    Lai, Wen-Ter
    Sheu, Sheng-Hsiung
    PLOS ONE, 2012, 7 (11):
  • [5] Quantification of Aortic Stiffness to Predict the Degree of Left Ventricular Diastolic Function
    Chung, Chang-Min
    Chu, Chi-Ming
    Chang, Shih-Tai
    Cheng, Hui-Wen
    Yang, Teng-Yao
    Wan, Po-Chang
    Pan, Kuo-Li
    Lin, Yu-Sheng
    Hsu, Jen-Te
    AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2010, 340 (06) : 468 - 473
  • [6] Association between coronary artery calcification and left ventricular diastolic dysfunction in elderly people
    Osawa, Kazuhiro
    Miyoshi, Toru
    Oe, Hiroki
    Sato, Shuhei
    Nakamura, Kazufumi
    Kohno, Kunihisa
    Morita, Hiroshi
    Kanazawa, Susumu
    Ito, Hiroshi
    HEART AND VESSELS, 2016, 31 (04) : 499 - 507
  • [7] Mismatch between arterial stiffness increase and left ventricular diastolic dysfunction
    Po-Chao Hsu
    Tsung-Hsien Lin
    Chee-Siong Lee
    Hsiang-Chun Lee
    Chun-Yuan Chu
    Ho-Ming Su
    Wen-Chol Voon
    Wen-Ter Lai
    Sheng-Hsiung Sheu
    Heart and Vessels, 2010, 25 : 485 - 492
  • [8] Mismatch between arterial stiffness increase and left ventricular diastolic dysfunction
    Hsu, Po-Chao
    Lin, Tsung-Hsien
    Lee, Chee-Siong
    Lee, Hsiang-Chun
    Chu, Chun-Yuan
    Su, Ho-Ming
    Voon, Wen-Chol
    Lai, Wen-Ter
    Sheu, Sheng-Hsiung
    HEART AND VESSELS, 2010, 25 (06) : 485 - 492
  • [9] Aortic valve calcification and increased stiffness of the proximal thoracic ascending aorta: association with left ventricular diastolic dysfunction and early chronic kidney disease
    Honma, Hiroshi
    Ohno, Tadaaki
    Tokita, Yukichi
    Matsuzaki, Tsuyako
    Fujimoto, Hiroyuki
    Yoshinaga, Aya
    Sato, Shoko
    Yokoshima, Tomoko
    Ito, Keiko
    Mizuno, Kyoichi
    JOURNAL OF MEDICAL ULTRASONICS, 2011, 38 (04) : 179 - 186
  • [10] The relationship of carotid arterial stiffness to left ventricular diastolic dysfunction in untreated hypertension
    Jaroch, Joanna
    Loboz-Grudzien, Krystyna
    Bociaga, Zbigniew
    Kowalska, Alicja
    Kruszynska, Ewa
    Wilczynska, Malgorzata
    Dudek, Krzysztof
    KARDIOLOGIA POLSKA, 2012, 70 (03) : 223 - 231