Nickel-Catalyzed C-Alkylation of Nitroalkanes with Unactivated Alkyl Iodides

被引：45

作者：

Rezazadeh, Sina ^{[1
]}

Devannah, Vijayarajan ^{[1
]}

Watson, Donald A. ^{[1
]}

机构：

[1] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 24期

关键词：

THERMAL REDOX CATALYSIS; KINETICS; HALIDES; BROMIDES; SUBSTITUTION; ALLYLATION; ESTERS;

D O I：

10.1021/jacs.7b04312

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary, and tertiary alkyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to diverse nitroalkanes.

引用

页码：8110 / 8113

页数：4

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