ECHOGENICITY OF THE COMMON CAROTID ARTERY INTIMA-MEDIA COMPLEX IN STROKE

被引：8
作者：
Aizawa, Kunihiko [1 ,2 ]
Elyas, Salim [1 ,2 ,3 ]
Adingupu, Damilola D. [1 ,2 ]
Casanova, Francesco [1 ,2 ]
Gooding, Kim M. [1 ,2 ]
Shore, Angela C. [1 ,2 ]
Strain, W. David [1 ,2 ,3 ]
Gates, Phillip E. [1 ,2 ]
机构：
[1] Univ Exeter, Sch Med, Diabet & Vasc Med Res Ctr, Barrack Rd, Exeter EX2 5AX, Devon, England
[2] NIHR Exeter Clin Res Facil, Exeter, Devon, England
[3] Royal Devon & Exeter NHS Fdn Trust, Exeter, Devon, England
来源：
ULTRASOUND IN MEDICINE AND BIOLOGY | 2016年 / 42卷 / 05期
关键词：
Ultrasound; Stroke; Intima-media thickness; Echogenicity; Carotid artery; CARDIOVASCULAR RISK-FACTORS; LIPID-RICH; ULTRASOUND; PLAQUES; ECHOLUCENCY; THICKNESS; EVENTS; ECHOGENECITY;
D O I：
10.1016/j.ultrasmedbio.2016.01.006
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
The grey-scale median of the common carotid artery intima-media complex (IM-GSM) characterizes arterial wall composition, and a low IM-GSM is associated with increased cardiovascular mortality in the elderly. We aimed to determine differences in the IM-GSM between a cohort with cerebrovascular disease and a healthy cohort. Eighty-two healthy individuals (control group: 63.2 +/- 8.7 y) and 96 patients with either stroke or transient ischemic attacks (CRVD group: 68.6 +/- 9.8 y) were studied. Common carotid artery intima-media thickness and IM-GSM obtained by ultrasound were analyzed using semi-automated edge-detection software. The IM-GSM was significantly lower in the CRVD group than in the control group (106 +/- 24 vs. 124 +/- 27 au, p < 0.001). The IM-GSM was similar for the infarct and non-infarct sides in CRVD. In the pooled cohort of all participants, the lower the quartile of IM-GSM, the greater were the carotid artery intima-media thickness and carotid artery remodeling. These results suggest the presence of an altered atherosclerotic phenotype in the intima-media complex of CRVD patients that can be detected by ultrasound. (C) 2016 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码：1130 / 1137
页数：8
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