Resolution of calcific brown fat necrosis associated with prostaglandin therapy for cyanotic congenital heart disease in neonates: report of two cases

被引：4

作者：

Miller, SF ^{[1
]}

机构：

[1] Hosp Sick Children, Dept Diagnost Imaging, Toronto, ON M5G 1X8, Canada

来源：

PEDIATRIC RADIOLOGY | 2004年 / 34卷 / 11期

关键词：

neonate; brown fat necrosis; calcification; congenital heart disease; prostaglandin;

D O I：

10.1007/s00247-004-1231-7

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Prostaglandin E1 (PGE1) administration for palliation of cyanotic congenital heart disease in neonates has been associated with radiographically visible necrosis of brown fat about the neck and shoulder girdles. However, the natural history of this process has not been described. We present two patients with cyanotic congenital heart disease, treated preoperatively with prostaglandin E2 (PGE2), both of whom developed dramatic calcific brown fat necrosis. This process slowly resolved over time in both patients.

引用

页码：919 / 923

页数：5

共 9 条

[1] BROWN ADIPOSE TISSUE AND HEAT PRODUCTION IN NEWBORN INFANT
AHERNE, W
HULL, D
[J]. JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1966, 91 (01): : 223 - &
[2] ATYPICAL BETA-ADRENOCEPTOR ON BROWN ADIPOCYTES AS TARGET FOR ANTI-OBESITY DRUGS
ARCH, JRS
AINSWORTH, AT
CAWTHORNE, MA
PIERCY, V
SENNITT, MV
THODY, VE
WILSON, C
WILSON, S
[J]. NATURE, 1984, 309 (5964) : 163 - 165
[3] Cohade C, 2003, J NUCL MED, V44, P170
[4] Fukuchi K, 2003, J NUCL MED, V44, P1582
[5] HEATON JM, 1972, J ANAT, V112, P35
[6] Okuyama C, 2003, J NUCL MED, V44, P1421
[7] Brown fat necrosis in the setting of congenital heart disease and prostaglandin E1 use: a case report
Raboi, CA
Smith, W
[J]. PEDIATRIC RADIOLOGY, 1999, 29 (01) : 61 - 63
[8] VISCERAL BROWN FAT NECROSIS IN POST-PERINATAL MORTALITY
STEPHENSON, TJ
VARIEND, S
[J]. JOURNAL OF CLINICAL PATHOLOGY, 1987, 40 (08) : 896 - 900
[9] Yeung HWD, 2003, J NUCL MED, V44, P1789

← 1 →