Biocatalytic hydrolysis of various anilides containing L-phenylalanine using Baker's yeast under starvation conditions

被引:0
作者
Noguchi, Takuya [1 ]
Daitoku, Hideyuki [1 ]
Satoh, Shin [1 ]
Kawashima, Yuya [1 ]
Imai, Nobuyuki [1 ]
机构
[1] Chiba Inst Sci, Fac Pharm, 15-8 Shiomi Cho, Choshi, Chiba 2880025, Japan
关键词
Biocatalyst; Baker's yeast; Hydrolysis; Anilide containing alpha-amino acid; Starvation conditions; ALPHA-AMINO-ACIDS; CONVENIENT PEPTIDE-SYNTHESIS; CARBOXYLIC-ACIDS; DIPEPTIDES; REDUCTION; AMIDATION; ALCOHOLS; ANALOGS; ESTERS;
D O I
10.1016/j.tetlet.2022.154130
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Biocatalytic hydrolysis of various anilides containing L-phenylalanine using Baker's yeast proceeded efficiently without sucrose under neutral conditions to afford the corresponding aniline derivatives in 26-60% yields. (C) 2022 Elsevier Ltd. All rights reserved.
引用
收藏
页数:3
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