Synthesis and characterization of novel phosphorictriamide derivatives with morpholine substituents:: Crystal structures of (CF3)C(O)NHP(O)(NC4H8O)2 and (p-Br-C6H4)C(O)NHP(O)(NC4H8O)2

Using phosphorus pentachloride as a substrate, carbacylamidophosphates of the general formula (R)C(O)NHP(O)(NC4H8O)(2), where R = CH2Cl I; CHCl2 II; CCl3 III; CF3 IV; p-Me-C6H4 V; p-Br-C6H4 VI; P-Cl-C6H4 VII, were prepared and characterized by H-1, P-31 and C-13 NMR, IR spectroscopy and elemental analysis. Different carboxylic amides attached to phosphorus nuclei affect on IR and NMR spectra. Three-bond coupling constants between phosphorus and carbon nucleus, (3)J(P,C-aliphatic) in the synthesized compounds, were greater than two-bond coupling constants, (2)J(P.C-aliphatic). The Structures of IV and VI were determined by single-crystal X-ray diffraction techniques. The compounds IV and VI formed centrosymmetric dimers via intermolecular N-(HO)-O-...=P hydrogen bonds.