Two new diterpenoid lactones isolated from Andrographis paniculata

被引：12
作者：
Wang Gui-Yang [1 ,2 ]
Wen Ting [1 ,2 ]
Liu Fei-Fei [1 ,2 ]
Tian Hai-Yan [1 ]
Fan Chun-Lin [1 ,2 ]
Huang Xiao-Jun [1 ,2 ]
Ye Wen-Cai [1 ,2 ]
Wang Ying [1 ,2 ]
机构：
[1] Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Coll Pharm, JNU HKUST Joint Lab Neurosci & Innovat Drug Res, Guangzhou 510632, Guangdong, Peoples R China
来源：
CHINESE JOURNAL OF NATURAL MEDICINES | 2017年 / 15卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Acanthaceae; Andrographis paniculata; Diterpenoid lactones; ENT-LABDANE DITERPENOIDS;
D O I：
10.1016/S1875-5364(17)30068-7
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
In the present study, two new diterpenoid lactones, 3-deoxy-andrographoside (1) and 14-deoxy-15-methoxy-andrographolide (2), were isolated from the aerial parts of Andrographis paniculata. Their structures were elucidated by combination of NMR, MS, and chemical methods. The configurations of 1 and 2 were established based on the analysis of ROESY data and single crystal X-ray diffraction experiment.
引用
收藏
页码：458 / 462
页数：5
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