Transient hypertnetabolism of the basal ganglia following perinatal hypoxia

被引：24

作者：

Batista, Carlos E. A.

Chugani, Harry T.

Juhasz, Csaba

Behen, Michael E.

Shankaran, Seetha

机构：

[1] Wayne State Univ, Div Pediat Neurol, PET Ctr, Childrens Hosp Michigan, Detroit, MI 48201 USA

[2] Wayne State Univ, Carman & Ann Adams Dept Pediat, Detroit, MI 48201 USA

[3] Wayne State Univ, Dept Neurol, Detroit, MI 48201 USA

[4] Wayne State Univ, Dept Radiol, Detroit, MI 48201 USA

来源：

PEDIATRIC NEUROLOGY | 2007年 / 36卷 / 05期

关键词：

D O I：

10.1016/j.pediatrneurol.2007.01.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Positron emission tomography can tie used to evaluate brain function following perinatal hypoxia. This case report demonstrates transient hypermetabolism in the basal ganglia detected by glucose metabolism positron emission tomography study in a newborn who suffered hypoxic-ischemic encephalopathy and developed dystonic cerebral palsy later. A scan repeated at 4 years of age showed severe hypometabolism in the lentiform nuclei and thalami. Transient hypermetabolism in the basal ganglia following perinatal hypoxia may be related to excitotoxic damage causing permanent neurological symptoms in the form of dystonic cerebral palsy. Thus, positron emission tomography can help predict this form of cerebral palsy in neonates. (C) 2007 by Elsevier Inc. All rights reserved.

引用

页码：330 / 333

页数：4

共 16 条

[1] Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury [J].