Understanding therapeutic targets in thrombotic thrombocytopenic purpura

被引：16

作者：

Joly, Berangere S. ^{[1
,2
]}

Vanhoorelbeke, Karen ^{[3
]}

Veyradier, Agnes ^{[1
,2
]}

机构：

[1] Univ Paris Diderot, Grp Hosp St Louis Lariboisiere, Assistance Publ Hop Paris, Serv Hematol Biol, 2 Rue Ambroise Pare, F-75010 Paris, France

[2] Univ Paris Diderot, Grp Hosp St Louis Lariboisiere, Assistance Publ Hop Paris, Inst Univ Hematol EA3518, 2 Rue Ambroise Pare, F-75010 Paris, France

[3] Katholieke Univ Leuven, IRF Life Sci, Lab Thrombosis Res, Campus Kulak Kortrijk, Kortrijk, Belgium

来源：

INTENSIVE CARE MEDICINE | 2017年 / 43卷 / 09期

基金：

欧盟地平线“2020”;

关键词：

VON-WILLEBRAND-FACTOR; FACTOR-CLEAVING PROTEASE; ADAMTS13; PATHOPHYSIOLOGY; ANTIBODIES; PLASMA; TTP;

D O I：

10.1007/s00134-016-4662-3

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

[No abstract available]

引用

页码：1398 / 1400

页数：3

共 19 条

[1] Recombinant ADAMTS 13 Attenuates Brain Injury After Intracerebral Hemorrhage [J].

Cai, Ping ;

Luo, Haiyu ;

Xu, Haochen ;

Zhu, Ximin ;

Xu, Wenfang ;

Dai, Yiqin ;

Xiao, Jin ;

Cao, Yongliang ;

Zhao, Yuwu ;

Zhao, Bing-Qiao ;

Fan, Wenying .

STROKE, 2015, 46 (09) :2647-2653

[2] N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice [J].

Chen, Junmei ;

Reheman, Adili ;

Gushiken, Francisca C. ;

Nolasco, Leticia ;

Fu, Xiaoyun ;

Moake, Joel L. ;

Ni, Heyu ;

Lopez, Jose A. .

JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (02) :593-603

[3] Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome [J].

Furlan, M ;

Robles, R ;

Galbusera, M ;

Remuzzi, G ;

Kyrle, PA ;

Brenner, B ;

Krause, M ;

Scharrer, I ;

Aumann, V ;

Mittler, U ;

Solenthaler, M ;

Lämmle, B .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (22) :1578-1584

[4] Corticosteroids and rituximab as adjunctive treatments for thrombotic thrombocytopenic purpura [J].

George, James N. .

AMERICAN JOURNAL OF HEMATOLOGY, 2012, 87 :S88-S91

[5] Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura [J].

Jian, Cui ;

Xiao, Juan ;

Gong, Lingjie ;

Skipwith, Christopher G. ;

Jin, Sheng-Yu ;

Kwaan, Hau C. ;

Zheng, X. Long .

BLOOD, 2012, 119 (16) :3836-3843

[6] Inhibition of von Willebrand factor by ARC1779 in patients with acute thrombotic thrombocytopenic purpura [J].

Jilina-Stohlawetz, Petra ;

Gorczyca, Monika E. ;

Jilma, Bernd ;

Siller-Matula, Jolanta ;

Gilbert, James C. ;

Knoebl, Paul .

THROMBOSIS AND HAEMOSTASIS, 2011, 105 (03) :545-552

[7] Child-onset and adolescent-onset acquired thrombotic thrombocytopenic purpura with severe ADAMTS13 deficiency: a cohort study of the French national registry for thrombotic microangiopathy [J].

Joly, Berangere S. ;

Stepanian, Alain ;

Leblanc, Thierry ;

Hajage, David ;

Chambost, Herve ;

Harambat, Jerome ;

Fouyssac, Fanny ;

Guigonis, Vincent ;

Leverger, Guy ;

Ulinski, Tim ;

Kwon, Theresa ;

Loirat, Chantal ;

Coppo, Paul ;

Veyradier, Agnes .

LANCET HAEMATOLOGY, 2016, 3 (11) :E537-E546

[8] Understanding organ dysfunction in thrombotic thrombocytopenic purpura [J].

Mannucci, Pier Mannuccio .

INTENSIVE CARE MEDICINE, 2015, 41 (04) :715-718

[9]

Mariotte E, 2016, LANCET HAEMATOL, V3, pE237, DOI [10.1016/S2352-3026(16)30018-7, 10.1016/s2352-3026(16)30018-7]

[10] Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura [J].

Peyvandi, Flora ;

Scully, Marie ;

Hovinga, Johanna A. Kremer ;

Cataland, Spero ;

Knoebl, Paul ;

Wu, Haifeng ;

Artoni, Andrea ;

Westwood, John-Paul ;

Taleghani, Magnus Mansouri ;

Jilma, Bernd ;

Callewaert, Filip ;

Ulrichts, Hans ;

Duby, Christian ;

Tersago, Dominique .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 374 (06) :511-522

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