Ethyl 6-[4-(dimethylamino)phenyl]-4-hydroxy-2-oxo-4-(trifluoromethyl)hexahydropyrimidine-5-carboxylate

被引:5
作者
Song, Xiao-Ping [1 ]
Li, Gong-Chun [1 ]
Wu, Chang-Zeng [1 ]
Yang, Feng-Ling [1 ]
机构
[1] Xuchang Univ, Coll Chem & Chem Engn, Xuchang 461000, Henan Province, Peoples R China
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2010年 / 66卷
关键词
MITOTIC KINESIN EG5;
D O I
10.1107/S1600536810013127
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The title compound, C(16)H(20)F(3)N(3)O(4), was prepared by reaction of 4-(dimethylamino) benzaldehyde, ethyl 4,4,4-trifluoro-3-oxobutanoate and urea. In the title molecule, the pyrimidine ring adopts a half-chair conformation and there is an intramolecular hydrogen bond (O-H center dot center dot center dot O). The crystal structure is stabilized by two types intermolecular hydrogen bonds (N-H center dot center dot center dot O and N-H center dot center dot center dot N).
引用
收藏
页码:O1083 / U151
页数:10
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