Genotoxicity of Zinc Oxide Nanoparticles in Plants Demonstrated Using Transgenic Arabidopsis thaliana

被引：8
作者：
Yang, Aifeng [1 ,2 ]
Wu, Jingjing [2 ]
Deng, Chenguang [2 ]
Wang, Ting [2 ]
Bian, Po [2 ]
机构：
[1] Hefei Univ Technol, Sch Management, Hefei, Anhui, Peoples R China
[2] Chinese Acad Sci, Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei Inst Phys Sci, POB 1138, Hefei 230031, Anhui, Peoples R China
来源：
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2018年 / 101卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Zinc oxide nanoparticles; Genotoxicity; Homologous recombination; Transcriptional gene silencing; Arabidopsis thaliana; HOMOLOGOUS RECOMBINATION; ENGINEERED NANOMATERIALS; EXPOSURE; GENE;
D O I：
10.1007/s00128-018-2420-7
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
As important members of earth biosphere, higher plants are inevitably exposed to nanoparticles (NP) released into the environment. Therefore, determining NP-induced phytotoxicity is ecologically important. Currently, researches into genotoxic effects of NP on plants are limited. In this study, Arabidopsis thaliana lines transgenic for homologous recombination (HR) and transcriptional gene silencing (TGS) reporter genes were for the first time adopted to assess the genotoxicity of Zinc oxide NP (ZnO-NP). Results showed that the root exposure to ZnO-NP led to increased HR and alleviation of TGS in the aerial tissues, indicative of the genotoxicity of ZnO-NP in plants. The increased Zn content after root exposure to ZnO-NP and the similar induction of HR and TGS alleviation after root exposure to equivalent Zn ions suggested that the genotoxicity of ZnO-NP might be mainly induced by Zn ions in aerial tissues that were transported from decomposed ZnO-NP in either medium or plant roots.
引用
收藏
页码：514 / 520
页数：7
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