Transcriptomic profile of intrinsically chemoresistant acute myeloid leukemia patients

被引：1
作者：
Horibata, Sachi [1 ]
机构：
[1] NCI, Lab Cell Biol, NIH, Bethesda, MD 20892 USA
来源：
MOLECULAR & CELLULAR ONCOLOGY | 2019年 / 6卷 / 06期
基金：
美国国家卫生研究院;
关键词：
Leukemia; intrinsic resistance; RNA-sequencing;
D O I：
10.1080/23723556.2019.1650631
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We recently identified three sub-populations of refractory acute myeloid leukemia (AML) patients with distinct intrinsic resistance mechanisms. Furthermore, we were able to risk-stratify the overall survival of the patients and identify patients who would likely benefit from alternative therapies.
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