Minimal hepatic encephalopathy: Consensus statement of a working party of the Indian National Association for Study of the Liver

被引：100

作者：

Dhiman, Radha K. ^{[1
]}

Saraswat, Vivek A. ^{[2
]}

Sharma, Barjesh K. ^{[3
]}

Sarin, Shiv K. ^{[4
]}

Chawla, Yogesh K. ^{[1
]}

Butterworth, Roger ^{[13
]}

Duseja, Ajay ^{[1
]}

Aggarwal, Rakesh ^{[2
]}

Amarapurkar, Deepak ^{[7
,8
]}

Sharma, Praveen ^{[4
]}

Madan, Kaushal ^{[4
]}

Shah, Samir ^{[9
]}

Seth, Avnish K. ^{[5
]}

Gupta, Rakesh K. ^{[2
]}

Koshy, Abraham ^{[10
]}

Rai, Ramesh R. ^{[11
]}

Dilawari, Jang B. ^{[14
]}

Mishra, Prakash ^{[12
]}

Acharya, Subrat K. ^{[6
]}

机构：

[1] Postgrad Inst Med Educ & Res, Dept Hepatol, Chandigarh 160012, India

[2] Sanjay Gandhi Postgrad Inst Med Sci, Dept Gastroenterol, Lucknow, Uttar Pradesh, India

[3] GB Pant Hosp, Dept Gastroenterol, New Delhi, India

[4] Inst Liver & Biliary Sci, New Delhi, India

[5] Army Hosp Res & Referral, New Delhi, India

[6] All India Inst Med Sci, New Delhi, India

[7] Bombay Hosp & Med Res Ctr, Bombay, Maharashtra, India

[8] Med Res Ctr, Bombay, Maharashtra, India

[9] Jaslok Hosp & Res Ctr, Bombay, Maharashtra, India

[10] Lakeshore Hosp, Dept Hepatol, Kochi, India

[11] Sawai Madho Singh Med Coll, Jaipur, Rajasthan, India

[12] Univ Allahabad, Motilal Nehru Med Coll, Allahabad 211002, Uttar Pradesh, India

[13] Univ Montreal, Hop St Luc, Neurosci Res Unit, Montreal, PQ, Canada

[14] Inver Clyde Royal Hosp, Dept Gastroenterol, Greenock, Scotland

来源：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | 2010年 / 25卷 / 06期

关键词：

critical clicker frequency; health-related quality of life; hepatic encephalopathy; lactulose; minimal hepatic encephalopathy; psychometric hepatic encephalopathy score; psychometry; RANDOMIZED CONTROLLED-TRIAL; CRITICAL FLICKER FREQUENCY; COMPUTERIZED PSYCHOMETRIC TESTS; MAGNETIC-RESONANCE-SPECTROSCOPY; PORTAL-VEIN OBSTRUCTION; INHIBITORY CONTROL TEST; NUMBER CONNECTION TEST; MOTOR-VEHICLE CRASHES; QUALITY-OF-LIFE; CIRRHOTIC-PATIENTS;

D O I：

10.1111/j.1440-1746.2010.06318.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatic encephalopathy (HE) is a major complication that develops in some form and at some stage in a majority of patients with liver cirrhosis. Overt HE occurs in approximately 30-45% of cirrhotic patients. Minimal HE (MHE), the mildest form of HE, is characterized by subtle motor and cognitive deficits and impairs health-related quality of life. The Indian National Association for Study of the Liver (INASL) set up a Working Party on MHE in 2008 with a mandate to develop consensus guidelines on various aspects of MHE relevant to clinical practice. Questions related to the definition of MHE, its prevalence, diagnosis, clinical characteristics, pathogenesis, natural history and treatment were addressed by the members of the Working Party.

引用

页码：1029 / 1041

页数：13

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