Synthesis of Benzoxazole and Benzimidazole Derivatives via Ligand-Free Copper(I)-Catalyzed Cross-Coupling Reaction of o-Halophenols or o-Haloanilines with Carbodiimides

被引：57

作者：

Shen, Guodong ^{[1
]}

Bao, Weiliang ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Zhejiang, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2010年 / 352卷 / 06期

关键词：

copper(I) catalysis; cross-coupling; heterocycles; ligand-free conditions; one-pot reaction; STREPTOMYCES SP 517-02; STRUCTURE-BASED DESIGN; N BOND FORMATION; C-N; EFFICIENT SYNTHESIS; CYTOTOXIC METABOLITE; CATALYZED SYNTHESIS; COPPER; ARYLATION; NITROGEN;

D O I：

10.1002/adsc.201000022

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel and efficient synthesis of benzoxazole and benzimidazole derivatives via a ligand-free, copper(I)-catalyzed, one-pot cascade process has been developed. A variety of carbodiimides coupled with o-halophenols or o-haloanilines to give the products in moderate to excellent yields under the mild conditions.

引用

页码：981 / 986

页数：6

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