Resistant human fasciolasis. Report of four patients

被引：40

作者：

Carlos Gil, Luis ^{[1
]}

Diaz, Alex ^{[1
]}

Rueda, Carlos ^{[2
]}

Martinez, Christian ^{[4
]}

Castillo, Douglas ^{[3
]}

Apt, Werner ^{[3
]}

机构：

[1] Univ Chile, Hosp Clin, Secc Gastroenterol, Santiago, Chile

[2] Hosp Victoria IX Reg, Clin Davila, Santiago, Chile

[3] Univ Chile, Fac Med, Programa Biol Celular & Mol, ICBM,Lab Parasitol Basico Clin, Santiago, Chile

[4] Univ Chile, Fac Med, Santiago, Chile

来源：

REVISTA MEDICA DE CHILE | 2014年 / 142卷 / 10期

关键词：

Cholangiography; Fasciola hepatica; Tridabendazole; TRICLABENDAZOLE; HEPATICA; FASCIOLIASIS; NITAZOXANIDE; EPIDEMIOLOGY; EFFICACY; CATTLE; SHEEP; PERU;

D O I：

10.4067/S0034-98872014001000014

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Human fascioliasis is a parasitic zoonosis that affects the liver of human and herbivorous animals. In chronic cases, its diagnosis is confirmed by direct visualization of parasitic eggs in stool examination, by positive testing for Fasciola hepatica antigens in stools, or by direct observation of parasites by endoscopic retrograde cholangiography or surgery. In acute cases, serological reactions as immunoblothing or detection of parasite antigens in the blood are useful. The treatment of choice is triclabendazole. However, parasite resistance in animals, as well as in man, has been reported to this drug. We report four patients in whom the parasitic infection persisted despite a course of treatment with triclabendazole.

引用

页码：1330 / 1333

页数：4

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